Oman Journal of Ophthalmology

Gene therapy within our vision: Illustrating the genetic paradigm

Gene therapy in ophthalmology

It has been more than a year since ophthalmologists and scientists under Dr. Robin Ali's team at the Moorsfield Eye Hospital and the Institute of Ophthalmology, University College London, successfully treated patients with a severely blinding disease, Leber's congenital amaurosis (LCA) using gene therapy. This success …

Changes in intraocular pressure after clear corneal phacoemulsification in normal patients

Purpose: To evaluate changes in intraocular pressure (IOP) after clear corneal phacoemulsification (CCP) in normal patients. Materials and methods: A prospective study including 273 normal patients selected for cataract extraction by CCP. Intraocular pressure was recorded on the 15(th) day, l(st), 2(nd), 3(rd) month an …

Epidemiological profile of fungal keratitis in urban population of West Bengal, India

Background: Corneal diseases are one of the major causes of visual loss and blindness, second only to cataract. Amongst corneal diseases, microbial keratitis is a major blinding disease. In some countries, fungal keratitis accounts for almost 50% of patients with culture-proven microbial keratitis. Aim: This study was …

The determinants of trichiasis recurrence differ at one and two years following lid surgery in Vietnam: A community-based intervention study

Aim: To compare determinants for recurrence of trichiasis at one and two years following lid surgery in Vietnam. Study design: Community-based intervention study. Methods: This study was carried out between 2000 and 2003 in four trachoma-endemic districts of Vietnam. Trained trichiasis surgeons performed modified Cueno …

Combined autologous and allograft limbal cell transplantation with penetrating keratoplasty in a case of chemical corneal burn patient

A patient with chemical corneal burn presented two months after the acute episode of chemical injury to his right eye (OD) and was diagnosed with severe limbal stem cell deficiency and with vascularized corneal opacity OD. Limbal cell transplantation and penetrating keratoplasty (PKP) was performed. The autologous and …

Vidi, vini, vinci: External ophthalmomyiasis infection that occurred, and was diagnosed and treated in a single day: A rare case report

Ophthalmomyiasis is an infestation of eye with larvae or maggots of certain flies. Oestrus ovis (sheep nasal botfly) belonging to family Oestridae is the most common cause of human myiasis. We describe here an acute presentation of a case of external ophthalmomyiasis, i.e., infestation of conjunctiva due to first insta …

Idiopathic choroidal neovascular membrane in a young female

A case of idiopathic choroidal neovascular membrane (CNVM) is described in a 17-year-old female patient. On initial examination her vision was counting fingers at one meter in the left eye (OS) and Fluorescein angiography showed a well-defined hyperfluorescent area corresponding to the CNVM. Intravitreal bevacizumab wa …

Orbital manifestations of Langerhans Cell Histiocytosis: A report of three cases

Langerhans Cell Histiocytosis (LCH) is a spectrum of disorders characterized by accumulation of histiocytes in various tissues. It is rarely encountered in ophthalmic practice and has an affinity for the orbit. We report three patients with LCH involving the lateral orbital wall, each with a different form of the condi …

Orbital venous-lymphatic malformation: Role of imaging