Review article Open access
The Effect of Proton Pump Inhibitors on Bone Mineralisation: A Systematic Review with Focus on PHOSPHO1
Objectives: Proton pump inhibitors (PPIs) are among the most widely prescribed drugs for long-term suppression of gastric acid. Though generally considered safe, increasing evidence links their use to altered bone metabolism. This systematic review investigates the hypothesis that PPI-induced inhibition on PHOSPHO1-a b …