Model-guided directed evolution seeks to identify high-fitness protein variants under limited oracle budgets. Protein language models (PLMs) provide rich representations for this task, but task-agnostic zero-shot scores can be misaligned with a target assay, while supervised search in high-dimensional embedding spaces …
Scientific discovery systems typically optimize experiments within a fixed hypothesis space. This creates a failure mode when all available candidates omit the same missing mechanism: candidate disagreement can collapse even while the model class is systematically wrong. We formulate experimental model-class revision, …
Portable mobile-manipulation demonstrations can help alleviate data scarcity for embodied intelligence, but obtaining reliable, low-cost, and robot-free motion supervision from RGB observations remains challenging. Existing approaches often rely on teleoperation or specialized devices equipped with additional sensing h …
Generating progressively harder reasoning problems requires synthesis procedures that adapt as the task distribution evolves. Existing task-level recursion reuses generated problems as seeds but leaves the construction harness unchanged. We present task-harness co-evolution, a framework for recursive harness self-impro …
Can changing only the language instruction redirect a VLA policy's end effector, or does the visually driven motion prior dominate? We present Atomic Motion Coordinate, a geometry-grounded coordinate for steerable and force-responsive manipulation. Each arm owns thirteen signed translation, rotation, and hold atoms gro …