Abstract
Acute dystonic reactions (ADR) are extrapyramidal effects that usually occur after the initiation of a wide variety of drugs or triggering factors besides neuroleptics. We report the case of a 54-year-old man who was admitted with an approximately 10-hour history of muscle twitching around the eyes, face and neck after he took the first dose of oral chloroquine phosphate (1 g [600 mg base]) prescribed for uncomplicated malaria. He was given intravenous diazepam (10 mg statum) followed by 10 mg of oral diazepam 3 times a day. The symptoms improved within 30 minutes of treatment, and he was discharged 14 hours later after a complete recovery.
Publication details
- DOI
- 10.18295/2075-0528.1511
- Journal
- Sultan Qaboos University Medical Journal, 13(3), 476-478
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Busari, O. A., Fadare, J., Gabriel, S., Olusegun, Elegbede, O., & Oladosu, Y. (2025). Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria. Sultan Qaboos University Medical Journal, 13(3), 476-478. https://doi.org/10.18295/2075-0528.1511
MLA 9
Busari, Olusegun A., et al. "Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria." Sultan Qaboos University Medical Journal, vol. 13, no. 3, 2025, pp. 476-478. https://doi.org/10.18295/2075-0528.1511.
Chicago (author–date)
Busari, Olusegun A., Joseph Fadare, Segun Gabriel, Olusegun, Olayide Elegbede, and Yusuf Oladosu. 2025. "Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria." Sultan Qaboos University Medical Journal 13 (3): 476-478. https://doi.org/10.18295/2075-0528.1511.
Harvard
Busari, O. A., Fadare, J., Gabriel, S., Olusegun, Elegbede, O. and Oladosu, Y. (2025) 'Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria', Sultan Qaboos University Medical Journal, 13(3), pp. 476-478. doi:10.18295/2075-0528.1511.
Vancouver
Busari OA, Fadare J, Gabriel S, Olusegun, Elegbede O, Oladosu Y. Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria. Sultan Qaboos University Medical Journal. 2025;13(3):476-478. doi:10.18295/2075-0528.1511
IEEE
O. A. Busari, J. Fadare, S. Gabriel, Olusegun, O. Elegbede, and Y. Oladosu, "Chloroquine-induced Acute Dystonic Reactions after a Standard Therapeutic Dose for Uncomplicated Malaria," Sultan Qaboos University Medical Journal, vol. 13, no. 3, pp. 476-478, 2025, doi: 10.18295/2075-0528.1511.