Abstract
Steven Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute life threatening mucocutaneous drug reactions. Several therapies have been used in the treatment of SJS/TEN but none of them have been established as the gold standard treatment, until now. Studies showed that cyclosporine (CsA) can be used off-label in TEN/SJS and has shown promising therapeutic effectiveness in such diseases. Here we report a 38 year-old woman who presented to Ar Rustaq Hospital, Rustaq, Oman in 2019 with SJS/TEN overlap and was treated successfully with CsA along with supportive management. This case report also includes a literature review on use of CsA in the treatment of SJS/TEN.
Publication details
- DOI
- 10.18295/squmj.4.2021.002
- Journal
- Sultan Qaboos University Medical Journal, 21(3), 491-494
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Al Rajaibi, R., Al Rumhi, T., & Al Abri, A. M. (2025). Carbamazepine Induced Steven Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review. Sultan Qaboos University Medical Journal, 21(3), 491-494. https://doi.org/10.18295/squmj.4.2021.002
MLA 9
Al Rajaibi, Raqiya, et al. "Carbamazepine Induced Steven Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review." Sultan Qaboos University Medical Journal, vol. 21, no. 3, 2025, pp. 491-494. https://doi.org/10.18295/squmj.4.2021.002.
Chicago (author–date)
Al Rajaibi, Raqiya, Thuraiya Al Rumhi, and Al Mur Al Abri. 2025. "Carbamazepine Induced Steven Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review." Sultan Qaboos University Medical Journal 21 (3): 491-494. https://doi.org/10.18295/squmj.4.2021.002.
Harvard
Al Rajaibi, R., Al Rumhi, T. and Al Abri, A. M. (2025) 'Carbamazepine Induced Steven Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review', Sultan Qaboos University Medical Journal, 21(3), pp. 491-494. doi:10.18295/squmj.4.2021.002.
Vancouver
Al Rajaibi R, Al Rumhi T, Al Abri AM. Carbamazepine Induced Steven Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review. Sultan Qaboos University Medical Journal. 2025;21(3):491-494. doi:10.18295/squmj.4.2021.002
IEEE
R. Al Rajaibi, T. Al Rumhi, and A. M. Al Abri, "Carbamazepine Induced Steven Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review," Sultan Qaboos University Medical Journal, vol. 21, no. 3, pp. 491-494, 2025, doi: 10.18295/squmj.4.2021.002.