[
    {
        "id": "osp-10438",
        "type": "article-journal",
        "title": "Carbamazepine Induced Steven Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review",
        "author": [
            {
                "family": "Al Rajaibi",
                "given": "Raqiya"
            },
            {
                "family": "Al Rumhi",
                "given": "Thuraiya"
            },
            {
                "family": "Al Abri",
                "given": "Al Mur"
            }
        ],
        "URL": "https://omanscience.com/en/articles/carbamazepine-induced-steven-johnson-syndrome-toxic-epidermal-necrolysis-overlap-treated-successfully-with-oral-cyclosporin-case-report-and-literature",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "21",
        "issue": "3",
        "page": "491-494",
        "DOI": "10.18295/squmj.4.2021.002",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Steven Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute life threatening mucocutaneous drug reactions. Several therapies have been used in the treatment of SJS/TEN but none of them have been established as the gold standard treatment, until now. Studies showed that cyclosporine (CsA) can be used off-label in TEN/SJS and has shown promising therapeutic effectiveness in such diseases. Here we report a 38 year-old woman who presented to Ar Rustaq Hospital, Rustaq, Oman in 2019 with SJS/TEN overlap and was treated successfully with CsA along with supportive management. This case report also includes a literature review on use of CsA in the treatment of SJS/TEN."
    }
]