Abstract

Vitamin D deficiency state is endemic to the Kashmir valley of the Indian subcontinent. Physicians often treat patients with high doses of vitamin D for various ailments and on occasion the prescribed doses far exceed the requirements of the patients. Ten cases of hypercalcemia due to vitamin D intoxication are presented with features of vomiting, polyuria, polydipsia, encephalopathy and renal dysfunction. All the patients had demonstrable hypercalcemia and vitamin D levels were high in nine of the 10 cases. The patients had received high doses of vitamin D and no other cause of hypercalcemia was identified. Treatment of hypercalcemia resulted in clinical recovery in nine cases. We conclude that hypervitaminosis D must be considered in the differential diagnosis of patients with hypercalcemia in endemically vitamin D deficient areas. A careful history and appropriate biochemical investigation will unravel the diagnosis in most of the cases.

Keywords

Subject

Publication details

DOI
10.5001/omj.2011.49
Journal
Oman Medical Journal
Publisher
Oman Medical Specialty Board
Open access
Gold open access

Cite this article

APA 7

Koul, P. A., Ahmad, S. H., Ahmad, F., Jan, R. A., Shah, S., & Khan, U. H. (2011). Vitamin D Toxicity in Adults: A Case Series from an Area with Endemic Hypovitaminosis D. Oman Medical Journal. https://doi.org/10.5001/omj.2011.49

MLA 9

Koul, Parvaiz A., et al. "Vitamin D Toxicity in Adults: A Case Series from an Area with Endemic Hypovitaminosis D." Oman Medical Journal, 2011. https://doi.org/10.5001/omj.2011.49.

Chicago (author–date)

Koul, Parvaiz A., Sheikh Hilal Ahmad, Feroze Ahmad, Rafi A. Jan, S.U. Shah, and Umar H. Khan. 2011. "Vitamin D Toxicity in Adults: A Case Series from an Area with Endemic Hypovitaminosis D." Oman Medical Journal. https://doi.org/10.5001/omj.2011.49.

Harvard

Koul, P. A., Ahmad, S. H., Ahmad, F., Jan, R. A., Shah, S. and Khan, U. H. (2011) 'Vitamin D Toxicity in Adults: A Case Series from an Area with Endemic Hypovitaminosis D', Oman Medical Journal. doi:10.5001/omj.2011.49.

Vancouver

Koul PA, Ahmad SH, Ahmad F, Jan RA, Shah S, Khan UH. Vitamin D Toxicity in Adults: A Case Series from an Area with Endemic Hypovitaminosis D. Oman Medical Journal. 2011. doi:10.5001/omj.2011.49

IEEE

P. A. Koul, S. H. Ahmad, F. Ahmad, R. A. Jan, S. Shah, and U. H. Khan, "Vitamin D Toxicity in Adults: A Case Series from an Area with Endemic Hypovitaminosis D," Oman Medical Journal, 2011, doi: 10.5001/omj.2011.49.