Advances in environmental and biomedical research through biotechnology have enhanced our knowledge and ability to effectively manage many issues affecting human health and the natural environment. Biotechnology has led to advancements in gene editing, regenerative medicine, and many other fields that contribute to hum …
Objectives: Pompe disease (glycogen storage disease type II) is a rare autosomal recessive lysosomal storage disease that is caused by acid alpha-glucosidase deficiency. Early enzyme replacement therapy can benefit infants with the disease but the diagnosis is complicated by the rarity of the disease and the heterogene …
Objectives: This study describes an unsupervised machine learning approach used to estimate the homeostatic model assessment-insulin resistance (HOMA-IR) cut-off for identifying subjects at risk of IR in a given ethnic group based on the clinical data of a representative sample. Methods: The approach was applied to ana …
Objectives: Design a machine learning-based prediction framework to predict the presence or absence of Systemic Lupus Erythematosus (SLE) in a cohort of Omani patients. Methods: Records of 219 patients from 2006 to 2019 were extracted from SQU Hospital electronic records, 138 patients have SLE, and the remaining 81 hav …
Objectives: Primary ciliary dyskinesia (PCD) is a disorder affecting the structure and function of the motile cilia of the respiratory system. Transmission electron microscopy is one method that can be used to examine ciliary ultrastructure in airway biopsies. Although the role of ultrastructural findings in PCD has be …
Objectives: Identification of the high risk alleles, genotypes and haplotypes of the human leukocyte antigens (HLA) in different populations is beneficial for understanding their roles in type 1 diabetes (T1D) pathogenesis and intervention practices. This study aimed to identify T1D-associated HLA gene alleles in the O …
Identification of fish species accurately is required to support efforts for conserving fishery biodiversity assessment and sustainable management. Recently, environmental DNA (eDNA) was suggested for regular monitoring of species for effective management of biodiversity. In Oman, molecular reference library representi …
This study aimed to screen for products containing Genetically Modified (GM) food in the Omani market using detection methods for the presence of Roundup Ready Soybean, Bt176 and MON810 maize in food products and to quantify it in positive samples using real time Polymerase Chain Reaction (PCR). A total of 100 food sam …