Research article Open access
Autosplenectomy of Sickle Cell Disease in Zaria, Nigeria: An Ultrasonographic Assessment
Objectives: During infancy and early childhood, the spleen commonly enlarges in patients with sickle cell anemia (SCA), and it thereafter undergoes progressive atrophy due to repeated episodes of vaso-occlusion and infarction, leading to autosplenectomy in adult life. However, this may not always be the case as some st …