Authors

Khalil Mahmoodi

Publications 2

Research article Open access

The C-565T Polymorphism (rs2422493) of the ATP-binding Cassette Transporter A1 Gene Contributes to the Development and Severity of Coronary Artery Disease in an Iranian Population

Khalil Mahmoodi, Koorosh Kamali, Habib Ghaznavi et al. · Oman Medical Journal · 2018 · 10.5001/omj.2018.57

Objectives: ATP-binding cassette transporter A1 (ABCA1) plays a pivotal role in reverse cholesterol transport from peripheral tissues back to the liver. Abnormalities in ABCA1 function may lead to dyslipidemia and coronary artery disease (CAD). We investigated the role of C-565T (rs2422493) promoter polymorphism of ABC …

Research article Open access

Evaluation of the Role of -137G/C Single Nucleotide Polymorphism (rs187238) and Gene Expression Levels of the IL-18 in Patients with Coronary Artery Disease

Fatemeh Hoseini, Sanaz Mahmazi, Khalil Mahmoodi et al. · Oman Medical Journal · 2018 · 10.5001/omj.2018.23

Objectives: Interleukin-18 (IL-18) is a proinflammatory and proatherogenic cytokine, and its genetic variations may contribute to the development of coronary artery disease (CAD). We sought to investigate the role of -137G/C polymorphism and gene expression levels of IL-18 in patients with CAD. Methods: The study popul …

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