Shoaib Al Zadjali

Appropriate Antiviral Therapy can Prevent Hepatitis B Reactivation and Progression in Chronic Myeloid Leukemia on Therapy with Tyrosine Kinase Inhibitors

Antiviral Therapy and Hepatitis B Reactivation Outcomes in Chronic Myeloid Leukemia Treated with Tyrosine Kinase Inhibitors: A Retrospective Cohort Study

Objectives: Viral Hepatitis reactivation can occur in patients receiving tyrosine kinase inhibitors (TKIs), with potentially fatal complications. We aimed to assess hepatitis reactivation in patients with chronic myeloid leukemia (CML) treated with TKIs. Methods: We retrospectively reviewed the clinical and laboratory …

Hyperglycemia and Obesity as the Key Drivers of Increased Colorectal Cancer Mortality in the North Africa and Middle East Region

Objectives: Colorectal cancer (CRC) age-standardized mortality rates (ASMR) are increasing in the North Africa and Middle East (NAME) region, in contrast to the global trend. While the upward trend of the CRC mortality in the NAME region is evident, the key drivers of this increase are still not fully established. We s …

IDH1 and IDH2 Gene Mutations in Omani Patients with Acute Myeloid Leukemia: Prognostic Significance and Clinic-pathologic Features

Objectives: We sought to define the prevalence of isocitrate dehydrogenase (IDH) mutations, evaluate the clinicopathologic impact of IDH mutations, assess the effect of IDH mutations on the response to the currently offered treatment for acute myeloid leukemia (AML) cases, and determine the impact of other common concu …