Research article Open access
HER2/neu Immunostaining in Invasive Breast Cancer: Analysis of False Positive Factors
Objectives: HER2/neu gene amplification by Fluorescent in situ hybridization and protein expression by immunohistochemistry have been used for prognosis and guidance for the treatment of invasive ductal carcinoma of the breast with Trastuzumab. False positive results are a significant problem where immunohistochemistry …