Research article Open access
A Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) test to Detect the Common Mutation (35delG) in the Connexin-26 Gene
Objective: To develop a polymerase chain reaction (PCR) based test for the detection of a common frame-shift mutation (35delG) in the connexin-26 (GJB2) gene, and to investigate the status of this mutation in Oman. Method: A PCR test, based on sitedirected mutagenesis, was developed for the 35delG mutation. A mutagenes …