Abstract
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Involvement of the nervous system, either primary or secondary, is common in SLE, and 19 different neuropsychiatric clinical syndromes have been recognised in association with the disease. Several pathophysiological mechanisms have been implicated in the pathogenesis of neuropsychiatric SLE (NPSLE), including vasculopathy, autoantibodies, and cytokine-mediated tissue injury. Careful evaluation of the patient is required to rule out secondary causes before attributing the neurological symptoms to SLE. Treatment depends on the nature and severity of NPSLE syndrome.
Publication details
- DOI
- 10.18295/2075-0528.1425
- Journal
- Sultan Qaboos University Medical Journal, 13(1), 19-25
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Alkhotani, A. (2025). Neuropsychiatric Lupus. Sultan Qaboos University Medical Journal, 13(1), 19-25. https://doi.org/10.18295/2075-0528.1425
MLA 9
Alkhotani, Amal. "Neuropsychiatric Lupus." Sultan Qaboos University Medical Journal, vol. 13, no. 1, 2025, pp. 19-25. https://doi.org/10.18295/2075-0528.1425.
Chicago (author–date)
Alkhotani, Amal. 2025. "Neuropsychiatric Lupus." Sultan Qaboos University Medical Journal 13 (1): 19-25. https://doi.org/10.18295/2075-0528.1425.
Harvard
Alkhotani, A. (2025) 'Neuropsychiatric Lupus', Sultan Qaboos University Medical Journal, 13(1), pp. 19-25. doi:10.18295/2075-0528.1425.
Vancouver
Alkhotani A. Neuropsychiatric Lupus. Sultan Qaboos University Medical Journal. 2025;13(1):19-25. doi:10.18295/2075-0528.1425
IEEE
A. Alkhotani, "Neuropsychiatric Lupus," Sultan Qaboos University Medical Journal, vol. 13, no. 1, pp. 19-25, 2025, doi: 10.18295/2075-0528.1425.