Abstract

There has been an extraordinary recent accumulation of information concerning the neurobiology and neuropharmacology of dopamine (DA) receptors in the mammalian central nervous system. Many new DA molecular entities have been cloned, their gene, peptide sequences and structures have been identified, their anatomical distributions in the mammalian brain described, and their pharmacology characterized. Progress has been made toward developing selective ligands and drug-candidates for different DA receptors. The new discoveries have greatly stimulated preclinical and clinical studies to explore the neuropharmacology of DA receptors and their implications in the neuropathophysiology of different neuropsychiatric diseases including schizophrenia, Parkinson’s disease and attention- deficit hyperactivity disorder. Accordingly, it seems timely to review the salient aspects of this specialized area of preclinical neuropharmacology and its relevance to clinical neuropsychiatry.

Publication details

DOI
10.18295/2075-0528.2587
Journal
Sultan Qaboos University Medical Journal, 3(2), 93-104
Publisher
Sultan Qaboos University
Open access
Gold open access
License
CC BY-ND 4.0

Cite this article

APA 7

Tarazi, F. I. (2025). Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases. Sultan Qaboos University Medical Journal, 3(2), 93-104. https://doi.org/10.18295/2075-0528.2587

MLA 9

Tarazi, Frank I. "Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases." Sultan Qaboos University Medical Journal, vol. 3, no. 2, 2025, pp. 93-104. https://doi.org/10.18295/2075-0528.2587.

Chicago (author–date)

Tarazi, Frank I. 2025. "Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases." Sultan Qaboos University Medical Journal 3 (2): 93-104. https://doi.org/10.18295/2075-0528.2587.

Harvard

Tarazi, F. I. (2025) 'Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases', Sultan Qaboos University Medical Journal, 3(2), pp. 93-104. doi:10.18295/2075-0528.2587.

Vancouver

Tarazi FI. Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases. Sultan Qaboos University Medical Journal. 2025;3(2):93-104. doi:10.18295/2075-0528.2587

IEEE

F. I. Tarazi, "Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases," Sultan Qaboos University Medical Journal, vol. 3, no. 2, pp. 93-104, 2025, doi: 10.18295/2075-0528.2587.