الملخص
There has been an extraordinary recent accumulation of information concerning the neurobiology and neuropharmacology of dopamine (DA) receptors in the mammalian central nervous system. Many new DA molecular entities have been cloned, their gene, peptide sequences and structures have been identified, their anatomical distributions in the mammalian brain described, and their pharmacology characterized. Progress has been made toward developing selective ligands and drug-candidates for different DA receptors. The new discoveries have greatly stimulated preclinical and clinical studies to explore the neuropharmacology of DA receptors and their implications in the neuropathophysiology of different neuropsychiatric diseases including schizophrenia, Parkinson’s disease and attention- deficit hyperactivity disorder. Accordingly, it seems timely to review the salient aspects of this specialized area of preclinical neuropharmacology and its relevance to clinical neuropsychiatry.
بيانات النشر
- المعرّف الرقمي
- 10.18295/2075-0528.2587
- المجلة
- مجلة جامعة السلطان قابوس الطبية, 3(2), 93-104
- الناشر
- جامعة السلطان قابوس
- وصول مفتوح
- وصول مفتوح ذهبي
- الترخيص
- CC BY-ND 4.0
اقتبس هذه المقالة
APA 7
Tarazi, F. I. (2025). Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases. Sultan Qaboos University Medical Journal, 3(2), 93-104. https://doi.org/10.18295/2075-0528.2587
MLA 9
Tarazi, Frank I. "Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases." Sultan Qaboos University Medical Journal, vol. 3, no. 2, 2025, pp. 93-104. https://doi.org/10.18295/2075-0528.2587.
شيكاغو (المؤلف–التاريخ)
Tarazi, Frank I. 2025. "Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases." Sultan Qaboos University Medical Journal 3 (2): 93-104. https://doi.org/10.18295/2075-0528.2587.
هارفارد
Tarazi, F. I. (2025) 'Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases', Sultan Qaboos University Medical Journal, 3(2), pp. 93-104. doi:10.18295/2075-0528.2587.
فانكوفر
Tarazi FI. Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases. Sultan Qaboos University Medical Journal. 2025;3(2):93-104. doi:10.18295/2075-0528.2587
IEEE
F. I. Tarazi, "Neuropharmacology of Dopamine Receptors: Implications in Neuropsychiatric Diseases," Sultan Qaboos University Medical Journal, vol. 3, no. 2, pp. 93-104, 2025, doi: 10.18295/2075-0528.2587.