Abstract
Aim: The aim was to report morphological and functional outcomes following modified early treatment diabetic retinopathy study (ETDRS) laser in diabetic macular edema (DME). Materials and methods: Structural and functional changes using spectral domain optical coherence tomography (OCT) and microperimetry (MP) were studied before and 4 months after laser in 37 eyes with clinically significant macular edema (ME) requiring modified ETDRS laser treatment. Paired t-test was used to compare pre and postlaser outcomes P < 0.05 was considered statistically significant. Results: Central foveal thickness showed a significant reduction after laser P = 0.004. There was a significant reduction in mean retinal thickness (MRT) and retinal volume in all the quadrants of ETDRS except for the temporal and nasal quadrants in outer 6 mm ring. Maximum reduction in MRT was seen in eyes with DME having neurosensory detachment (382.66 μ to 292.61 μ). Retinal sensitivities reduced in all quadrants following laser, however, fixation patterns showed improvements. The change in VA was positively correlated to change in MRT (r = 0.468, P = 0.032). Conclusion: Laser not only causes structural benefits such as reduction of retinal thickness and volume, it also causes improvement of fixation patterns.
Keywords
Publication details
- DOI
- 10.4103/0974-620x.159252
- Journal
- Oman Journal of Ophthalmology, 8(2), 92-96
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Raman, R., Santhanam, K., Gella, L., Pal, B. P., & Sharma, T. (2015). Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema. Oman Journal of Ophthalmology, 8(2), 92-96. https://doi.org/10.4103/0974-620x.159252
MLA 9
Raman, Rajiv, et al. "Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema." Oman Journal of Ophthalmology, vol. 8, no. 2, 2015, pp. 92-96. https://doi.org/10.4103/0974-620x.159252.
Chicago (author–date)
Raman, Rajiv, Kiruthika Santhanam, Laxmi Gella, Bikramjit P Pal, and Tarun Sharma. 2015. "Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema." Oman Journal of Ophthalmology 8 (2): 92-96. https://doi.org/10.4103/0974-620x.159252.
Harvard
Raman, R., Santhanam, K., Gella, L., Pal, B. P. and Sharma, T. (2015) 'Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema', Oman Journal of Ophthalmology, 8(2), pp. 92-96. doi:10.4103/0974-620x.159252.
Vancouver
Raman R, Santhanam K, Gella L, Pal BP, Sharma T. Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema. Oman Journal of Ophthalmology. 2015;8(2):92-96. doi:10.4103/0974-620x.159252
IEEE
R. Raman, K. Santhanam, L. Gella, B. P. Pal, and T. Sharma, "Morphological and functional outcomes following modified early treatment diabetic retinopathy study laser in diabetic macular edema," Oman Journal of Ophthalmology, vol. 8, no. 2, pp. 92-96, 2015, doi: 10.4103/0974-620x.159252.