Abstract
We read the report on ‘Primary Hepatic Lymphoma Mimicking Cholangiocarcinoma’ published in the July 2017 issue of the Oman Medical Journal with great interest. In fact, both primary hepatic lymphoma and cholangiocarcinoma might result in highly similar clinical presentation and are sporadically mentioned in the literature. Here, we would like to discuss a possible way to differentiate between both disorders using serum alkaline phosphatase (ALP) isoenzyme electrophoresis, a simple laboratory test. Based on a previous report from Thailand, the significant elevation of specific fast liver isoenzyme of ALP can be observed in malignant tumors of the biliary tract. For primary hepatic lymphoma, additional atypical bone-like isoenzyme of ALP might be observed. Since the ALP isoenzyme test can be easily done and provide the result within a short time, it should be considered a tool to help confirm the diagnosis of cholangiocarcinoma.
Publication details
- DOI
- 10.5001/omj.2018.83
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Yasri, S., & Wiwanitkit, V. (2018). How to Discriminate Between Primary Hepatic Lymphoma and Cholangiocarcinoma. Oman Medical Journal. https://doi.org/10.5001/omj.2018.83
MLA 9
Yasri, Sora, and Viroj Wiwanitkit. "How to Discriminate Between Primary Hepatic Lymphoma and Cholangiocarcinoma." Oman Medical Journal, 2018. https://doi.org/10.5001/omj.2018.83.
Chicago (author–date)
Yasri, Sora, and Viroj Wiwanitkit. 2018. "How to Discriminate Between Primary Hepatic Lymphoma and Cholangiocarcinoma." Oman Medical Journal. https://doi.org/10.5001/omj.2018.83.
Harvard
Yasri, S. and Wiwanitkit, V. (2018) 'How to Discriminate Between Primary Hepatic Lymphoma and Cholangiocarcinoma', Oman Medical Journal. doi:10.5001/omj.2018.83.
Vancouver
Yasri S, Wiwanitkit V. How to Discriminate Between Primary Hepatic Lymphoma and Cholangiocarcinoma. Oman Medical Journal. 2018. doi:10.5001/omj.2018.83
IEEE
S. Yasri, and V. Wiwanitkit, "How to Discriminate Between Primary Hepatic Lymphoma and Cholangiocarcinoma," Oman Medical Journal, 2018, doi: 10.5001/omj.2018.83.