Abstract
Objectives: This study was undertaken to determine the effect of subacute exposure of peracetic acid on lipid peroxidation and hepatic enzymes in Wistar rats. Methods: 48 male animals in Treatment Group I, II and III received 0.2%, 2% and 20% peracetic acid daily for 2 and 4 weeks. Results: Serum malondialdehyde increased and Alanine Transaminase and Aspartate Transaminase decreased significantly in groups 2 and 3, compared to the control group. The malondialdehyde, Alanine Transaminase and Aspartate Transaminase with 0.2% and 2% doses of peracetic acid for 2 weeks do not lead to the alteration of malondialdehyde and enzyme activities. Conclusion: This study demonstrated that the enhancement of malondialdehyde could provide an oxidative damage induced by disinfectant peroxidation at 20% and 2% doses at 2 and 4 weeks. The consumption of peroxidation with 20% for 2 weeks and 2% for 4 weeks can cause the increase of malondialdehyde and the decrease of enzyme activities, respectively.
Keywords
Subject
Publication details
- DOI
- 10.5001/omj.2010.77
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Marjani, A., Golalipour, M. J., & Gharravi, A. M. (2010). The Effects of Subacute Exposure of Peracetic Acid on Lipid Peroxidation and Hepatic Enzymes in Wistar Rats. Oman Medical Journal. https://doi.org/10.5001/omj.2010.77
MLA 9
Marjani, Abdoljalal, et al. "The Effects of Subacute Exposure of Peracetic Acid on Lipid Peroxidation and Hepatic Enzymes in Wistar Rats." Oman Medical Journal, 2010. https://doi.org/10.5001/omj.2010.77.
Chicago (author–date)
Marjani, Abdoljalal, Mohammad J. Golalipour, and Anneh M. Gharravi. 2010. "The Effects of Subacute Exposure of Peracetic Acid on Lipid Peroxidation and Hepatic Enzymes in Wistar Rats." Oman Medical Journal. https://doi.org/10.5001/omj.2010.77.
Harvard
Marjani, A., Golalipour, M. J. and Gharravi, A. M. (2010) 'The Effects of Subacute Exposure of Peracetic Acid on Lipid Peroxidation and Hepatic Enzymes in Wistar Rats', Oman Medical Journal. doi:10.5001/omj.2010.77.
Vancouver
Marjani A, Golalipour MJ, Gharravi AM. The Effects of Subacute Exposure of Peracetic Acid on Lipid Peroxidation and Hepatic Enzymes in Wistar Rats. Oman Medical Journal. 2010. doi:10.5001/omj.2010.77
IEEE
A. Marjani, M. J. Golalipour, and A. M. Gharravi, "The Effects of Subacute Exposure of Peracetic Acid on Lipid Peroxidation and Hepatic Enzymes in Wistar Rats," Oman Medical Journal, 2010, doi: 10.5001/omj.2010.77.