Abstract
Aflatoxin B1 (AFB1) is a mycotoxin which can cause serious toxicity to animals and humans. The aim of this study was to investigate the effects of AFB1 in Aphanius dispar fish and measure residues in tissues after in vivo exposure. Aphanius dispar were fed diets containing 50, 100, 150 and 200 µg AFB1/kg for 10, 20 and 30 days. At the end of the experiment, the liver and gills were dissected out and processed for light and electron microscopy. During the experiment, no external changes or unusual behavior were observed in the fish. Histopathological and ultrastructural changes in liver appeared under all four treatments: 50, 100, 150 and 200 µg AFB1/kg. Gill tissues were affected at high doses of 100,150 and 200 µg AFB1/kg. Accumulation of AFB1 residues in liver and gill tissues was found to be related to a dose and duration of exposure.
Keywords
Publication details
- DOI
- 10.24200/squjs.vol20iss1pp1-10
- Journal
- Sultan Qaboos University Journal for Science, 20(1), 1
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY 4.0
Cite this article
APA 7
Al-Azri, H. H., Baomar, T., Elshafie, A. E., & Barry, M. J. (2015). Histopathological and Ultrastructural Changes in the Liver and Gills of the Killifish Aphanius Dispar (Cyprinodontidae) Exposed to Aflatoxin B1. Sultan Qaboos University Journal for Science, 20(1), 1. https://doi.org/10.24200/squjs.vol20iss1pp1-10
MLA 9
Al-Azri, Horiya H., et al. "Histopathological and Ultrastructural Changes in the Liver and Gills of the Killifish Aphanius Dispar (Cyprinodontidae) Exposed to Aflatoxin B1." Sultan Qaboos University Journal for Science, vol. 20, no. 1, 2015, pp. 1. https://doi.org/10.24200/squjs.vol20iss1pp1-10.
Chicago (author–date)
Al-Azri, Horiya H., Taher Baomar, Abdulkadir E. Elshafie, and Michael J. Barry. 2015. "Histopathological and Ultrastructural Changes in the Liver and Gills of the Killifish Aphanius Dispar (Cyprinodontidae) Exposed to Aflatoxin B1." Sultan Qaboos University Journal for Science 20 (1): 1. https://doi.org/10.24200/squjs.vol20iss1pp1-10.
Harvard
Al-Azri, H. H., Baomar, T., Elshafie, A. E. and Barry, M. J. (2015) 'Histopathological and Ultrastructural Changes in the Liver and Gills of the Killifish Aphanius Dispar (Cyprinodontidae) Exposed to Aflatoxin B1', Sultan Qaboos University Journal for Science, 20(1), pp. 1. doi:10.24200/squjs.vol20iss1pp1-10.
Vancouver
Al-Azri HH, Baomar T, Elshafie AE, Barry MJ. Histopathological and Ultrastructural Changes in the Liver and Gills of the Killifish Aphanius Dispar (Cyprinodontidae) Exposed to Aflatoxin B1. Sultan Qaboos University Journal for Science. 2015;20(1):1. doi:10.24200/squjs.vol20iss1pp1-10
IEEE
H. H. Al-Azri, T. Baomar, A. E. Elshafie, and M. J. Barry, "Histopathological and Ultrastructural Changes in the Liver and Gills of the Killifish Aphanius Dispar (Cyprinodontidae) Exposed to Aflatoxin B1," Sultan Qaboos University Journal for Science, vol. 20, no. 1, pp. 1, 2015, doi: 10.24200/squjs.vol20iss1pp1-10.