Abstract
Disseminated herpes simplex virus (HSV) is a known fatal condition in neonates and immunocompromised patients. However, very few cases have been reported in an immunocompetent host. We report a 1-year-old female child who presented to a children's hospital in Riyadh, Saudi Arabia, in 2022. She was previously healthy and presented with febrile illness associated with decrease conscious level. Upon examination, the patient had markedly elevated liver enzymes. A cerebrospinal fluid (CSF) polymerase chain reaction (PCR) finding of HSV as well as positive HSV IgM serology resulted in a diagnosis of disseminated HSV (encephalitis/hepatitis). She received acyclovir course and during follow-up for 1 year showed excellent developmental outcome.
Subject
Publication details
- DOI
- 10.18295/squmj.6.2024.042
- Journal
- Sultan Qaboos University Medical Journal, 25(1), 137-140
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Adedeji, I. A., Abdullahi, A., Abusrair, A. S., Fatimah, & Alshehri, M. (2025). Disseminated Herpes Simplex Virus-1 in Previously Healthy Child Without Skin Rash: Case report and literature review. Sultan Qaboos University Medical Journal, 25(1), 137-140. https://doi.org/10.18295/squmj.6.2024.042
MLA 9
Adedeji, Idris A., et al. "Disseminated Herpes Simplex Virus-1 in Previously Healthy Child Without Skin Rash: Case report and literature review." Sultan Qaboos University Medical Journal, vol. 25, no. 1, 2025, pp. 137-140. https://doi.org/10.18295/squmj.6.2024.042.
Chicago (author–date)
Adedeji, Idris A., Abdulrahim Abdullahi, Abdulmohsen S. Abusrair, Fatimah, and Mohamed Alshehri. 2025. "Disseminated Herpes Simplex Virus-1 in Previously Healthy Child Without Skin Rash: Case report and literature review." Sultan Qaboos University Medical Journal 25 (1): 137-140. https://doi.org/10.18295/squmj.6.2024.042.
Harvard
Adedeji, I. A., Abdullahi, A., Abusrair, A. S., Fatimah and Alshehri, M. (2025) 'Disseminated Herpes Simplex Virus-1 in Previously Healthy Child Without Skin Rash: Case report and literature review', Sultan Qaboos University Medical Journal, 25(1), pp. 137-140. doi:10.18295/squmj.6.2024.042.
Vancouver
Adedeji IA, Abdullahi A, Abusrair AS, Fatimah, Alshehri M. Disseminated Herpes Simplex Virus-1 in Previously Healthy Child Without Skin Rash: Case report and literature review. Sultan Qaboos University Medical Journal. 2025;25(1):137-140. doi:10.18295/squmj.6.2024.042
IEEE
I. A. Adedeji, A. Abdullahi, A. S. Abusrair, Fatimah, and M. Alshehri, "Disseminated Herpes Simplex Virus-1 in Previously Healthy Child Without Skin Rash: Case report and literature review," Sultan Qaboos University Medical Journal, vol. 25, no. 1, pp. 137-140, 2025, doi: 10.18295/squmj.6.2024.042.