Abstract
Objectives: We sought to evaluate the role of bronchoscopy-related procedures such as bronchoalveolar lavage (BAL), bronchial wash (BW), bronchial brush (B brush), transbronchial biopsy (TBB), and post-bronchoscopy sputum (PBS), alone or in combination, in the rapid diagnosis of negative sputum smear disseminated tuberculosis (TB). Methods: We performed a secondary post hoc analysis of data collected from our previous study entitled “Disseminated tuberculosis among adult patients admitted to Hamad General Hospital, Qatar: A five-year hospital-based study” with a modified objective. Results: We identified 27 patients. BAL fluid was positive for acid-fast bacilli (AFB) smear in 7/27 (25.9%) patients and were culture-positive for Myobacterium tuberculosis in 17/27 (63.0%) cases, while BW collections were smear-positive in 9/27 (33.3%) cases and culture-positive for M. tuberculosis in 18/27 (66.7%) cases. TBB showed caseating granulomas in 10/16 (62.5%) cases and one case of non-caseating granuloma (6.3%). PBS was positive for AFB in 4/8 (50.0%) patients. The combination of these procedures enabled us to diagnose disseminated TB rapidly in 22 (81.5%) cases. Conclusions: Bronchoscopy proved to be an effective method for the rapid diagnosis of disseminated TB in patients in whom sputum smear microscopy was negative.
Keywords
Publication details
- DOI
- 10.5001/omj.2020.05
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Khan, F. Y., & Aladab, A. H. (2020). Role of Fiberoptic Bronchoscopy in the Rapid Diagnosis of Sputum Smear-negative Disseminated Tuberculosis with Pulmonary Miliary Infiltrates. Oman Medical Journal. https://doi.org/10.5001/omj.2020.05
MLA 9
Khan, Fahmi Yousef, and Aisha Hussein Aladab. "Role of Fiberoptic Bronchoscopy in the Rapid Diagnosis of Sputum Smear-negative Disseminated Tuberculosis with Pulmonary Miliary Infiltrates." Oman Medical Journal, 2020. https://doi.org/10.5001/omj.2020.05.
Chicago (author–date)
Khan, Fahmi Yousef, and Aisha Hussein Aladab. 2020. "Role of Fiberoptic Bronchoscopy in the Rapid Diagnosis of Sputum Smear-negative Disseminated Tuberculosis with Pulmonary Miliary Infiltrates." Oman Medical Journal. https://doi.org/10.5001/omj.2020.05.
Harvard
Khan, F. Y. and Aladab, A. H. (2020) 'Role of Fiberoptic Bronchoscopy in the Rapid Diagnosis of Sputum Smear-negative Disseminated Tuberculosis with Pulmonary Miliary Infiltrates', Oman Medical Journal. doi:10.5001/omj.2020.05.
Vancouver
Khan FY, Aladab AH. Role of Fiberoptic Bronchoscopy in the Rapid Diagnosis of Sputum Smear-negative Disseminated Tuberculosis with Pulmonary Miliary Infiltrates. Oman Medical Journal. 2020. doi:10.5001/omj.2020.05
IEEE
F. Y. Khan, and A. H. Aladab, "Role of Fiberoptic Bronchoscopy in the Rapid Diagnosis of Sputum Smear-negative Disseminated Tuberculosis with Pulmonary Miliary Infiltrates," Oman Medical Journal, 2020, doi: 10.5001/omj.2020.05.