Abstract
Granulomatosis with polyangiitis (GPA) is a rare autoimmune disease with multiâ€system involvement. It involves the upper respiratory tract, lungs and kidneys. A 36-year-old female patient presented with complaints of low-grade fever, dry cough and loss of appetite initially followed by dyspnea, purpuric skin lesions, right lower limb swelling with pain and redness. Her chest radiograph revealed right upper lobe cavitary lesion with consolidation in right lower lobe. Mycobacterium tuberculosis was detected in sputum and Broncho alveolar lavage (BAL) via Cartridge based nucleic acid amplification assay (CB-NAAT). Later, Computed Tomography Pulmonary Angiography (CTPA) revealed bilateral pulmonary artery thromboembolism. Furthermore, her C-ANCA was positive, serum creatinine was rising, urine microscopy had red cell casts and lower limb venous doppler revealed DVT. Histopathological examination of the skin lesion revealed vasculitis. Based on the above findings, diagnosis of GPA was comfortably made. Patient improved with pulse steroids, cyclophosphamide, anticoagulants and anti-tuberculous therapy (ATT). Keywords: Granulomatosis with polyangiitis (GPA), Pulmonary Tuberculosis, Pulmonary thrombo-embolism, deep venous thrombosis, vasculitis, c-ANCA.
Subject
Publication details
- DOI
- 10.18295/squmj.12.2023.095
- Journal
- Sultan Qaboos University Medical Journal, 24(3), 399-401
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Pavirala, S. T., Khurana, A., Kadian, K., & Goyal, A. (2025). Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble. Sultan Qaboos University Medical Journal, 24(3), 399-401. https://doi.org/10.18295/squmj.12.2023.095
MLA 9
Pavirala, Sai T., et al. "Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble." Sultan Qaboos University Medical Journal, vol. 24, no. 3, 2025, pp. 399-401. https://doi.org/10.18295/squmj.12.2023.095.
Chicago (author–date)
Pavirala, Sai T., Alkesh Khurana, Kirti Kadian, and Abhishek Goyal. 2025. "Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble." Sultan Qaboos University Medical Journal 24 (3): 399-401. https://doi.org/10.18295/squmj.12.2023.095.
Harvard
Pavirala, S. T., Khurana, A., Kadian, K. and Goyal, A. (2025) 'Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble', Sultan Qaboos University Medical Journal, 24(3), pp. 399-401. doi:10.18295/squmj.12.2023.095.
Vancouver
Pavirala ST, Khurana A, Kadian K, Goyal A. Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble. Sultan Qaboos University Medical Journal. 2025;24(3):399-401. doi:10.18295/squmj.12.2023.095
IEEE
S. T. Pavirala, A. Khurana, K. Kadian, and A. Goyal, "Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble," Sultan Qaboos University Medical Journal, vol. 24, no. 3, pp. 399-401, 2025, doi: 10.18295/squmj.12.2023.095.