الملخص
Granulomatosis with polyangiitis (GPA) is a rare autoimmune disease with multiâ€system involvement. It involves the upper respiratory tract, lungs and kidneys. A 36-year-old female patient presented with complaints of low-grade fever, dry cough and loss of appetite initially followed by dyspnea, purpuric skin lesions, right lower limb swelling with pain and redness. Her chest radiograph revealed right upper lobe cavitary lesion with consolidation in right lower lobe. Mycobacterium tuberculosis was detected in sputum and Broncho alveolar lavage (BAL) via Cartridge based nucleic acid amplification assay (CB-NAAT). Later, Computed Tomography Pulmonary Angiography (CTPA) revealed bilateral pulmonary artery thromboembolism. Furthermore, her C-ANCA was positive, serum creatinine was rising, urine microscopy had red cell casts and lower limb venous doppler revealed DVT. Histopathological examination of the skin lesion revealed vasculitis. Based on the above findings, diagnosis of GPA was comfortably made. Patient improved with pulse steroids, cyclophosphamide, anticoagulants and anti-tuberculous therapy (ATT). Keywords: Granulomatosis with polyangiitis (GPA), Pulmonary Tuberculosis, Pulmonary thrombo-embolism, deep venous thrombosis, vasculitis, c-ANCA.
بيانات النشر
- المعرّف الرقمي
- 10.18295/squmj.12.2023.095
- المجلة
- مجلة جامعة السلطان قابوس الطبية, 24(3), 399-401
- الناشر
- جامعة السلطان قابوس
- وصول مفتوح
- وصول مفتوح ذهبي
- الترخيص
- CC BY-ND 4.0
اقتبس هذه المقالة
APA 7
Pavirala, S. T., Khurana, A., Kadian, K., & Goyal, A. (2025). Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble. Sultan Qaboos University Medical Journal, 24(3), 399-401. https://doi.org/10.18295/squmj.12.2023.095
MLA 9
Pavirala, Sai T., et al. "Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble." Sultan Qaboos University Medical Journal, vol. 24, no. 3, 2025, pp. 399-401. https://doi.org/10.18295/squmj.12.2023.095.
شيكاغو (المؤلف–التاريخ)
Pavirala, Sai T., Alkesh Khurana, Kirti Kadian, and Abhishek Goyal. 2025. "Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble." Sultan Qaboos University Medical Journal 24 (3): 399-401. https://doi.org/10.18295/squmj.12.2023.095.
هارفارد
Pavirala, S. T., Khurana, A., Kadian, K. and Goyal, A. (2025) 'Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble', Sultan Qaboos University Medical Journal, 24(3), pp. 399-401. doi:10.18295/squmj.12.2023.095.
فانكوفر
Pavirala ST, Khurana A, Kadian K, Goyal A. Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble. Sultan Qaboos University Medical Journal. 2025;24(3):399-401. doi:10.18295/squmj.12.2023.095
IEEE
S. T. Pavirala, A. Khurana, K. Kadian, and A. Goyal, "Coexistence of Pulmonary Thromboembolism, Pulmonary Tuberculosis and Granulomatosis with Polyangiitis: A flimsy triple dribble," Sultan Qaboos University Medical Journal, vol. 24, no. 3, pp. 399-401, 2025, doi: 10.18295/squmj.12.2023.095.