Abstract

Thalassaemia, a hereditary blood disorder, remains under-recognised due to limited awareness, particularly among young people. This scoping review aimed to evaluate the characteristics and effectiveness of premarital thalassaemia educational interventions globally. Following PRISMA-ScR guidelines, six databases were searched for English-language studies targeting adolescents and young adults. Eight studies met the inclusion criteria, and data were extracted using a standardised form adapted from the Joanna Briggs Institute, focusing on intervention characteristics, outcomes and key findings. Most studies involved school students and young adults from culturally diverse, resource-limited settings. The interventions—traditional, technology-based or culturally adapted—consistently improved knowledge (P < 0.001). However, behavioural outcomes, such as increased uptake of screening, were inconsistent. While educational strategies enhanced knowledge effectively, socio-cultural barriers limited the translation into behavioural changes. These findings support the need for future interventions to integrate behavioural change theories, leverage digital tools and address cultural sensitivities to improve their overall impact.

Publication details

DOI
10.18295/2075-0528.2908
Journal
Sultan Qaboos University Medical Journal, 25(1), 773-783
Publisher
Sultan Qaboos University
Open access
Gold open access
License
CC BY-ND 4.0

Cite this article

APA 7

Anwar, M. N., Abdullah, N. N., Roslan, D., & Ruzlin, A. N. (2025). Characteristics and Effectiveness of Premarital Thalassaemia Educational Interventions Worldwide: A scoping review. Sultan Qaboos University Medical Journal, 25(1), 773-783. https://doi.org/10.18295/2075-0528.2908

MLA 9

Anwar, Maisarah N., et al. "Characteristics and Effectiveness of Premarital Thalassaemia Educational Interventions Worldwide: A scoping review." Sultan Qaboos University Medical Journal, vol. 25, no. 1, 2025, pp. 773-783. https://doi.org/10.18295/2075-0528.2908.

Chicago (author–date)

Anwar, Maisarah N., Nik Nairan Abdullah, Dalila Roslan, and Aimi N.M. Ruzlin. 2025. "Characteristics and Effectiveness of Premarital Thalassaemia Educational Interventions Worldwide: A scoping review." Sultan Qaboos University Medical Journal 25 (1): 773-783. https://doi.org/10.18295/2075-0528.2908.

Harvard

Anwar, M. N., Abdullah, N. N., Roslan, D. and Ruzlin, A. N. (2025) 'Characteristics and Effectiveness of Premarital Thalassaemia Educational Interventions Worldwide: A scoping review', Sultan Qaboos University Medical Journal, 25(1), pp. 773-783. doi:10.18295/2075-0528.2908.

Vancouver

Anwar MN, Abdullah NN, Roslan D, Ruzlin AN. Characteristics and Effectiveness of Premarital Thalassaemia Educational Interventions Worldwide: A scoping review. Sultan Qaboos University Medical Journal. 2025;25(1):773-783. doi:10.18295/2075-0528.2908

IEEE

M. N. Anwar, N. N. Abdullah, D. Roslan, and A. N. Ruzlin, "Characteristics and Effectiveness of Premarital Thalassaemia Educational Interventions Worldwide: A scoping review," Sultan Qaboos University Medical Journal, vol. 25, no. 1, pp. 773-783, 2025, doi: 10.18295/2075-0528.2908.