Abstract

Hereditary angioedema (HAE) is a rare disorder caused by a deficiency of C1 esterase inhibitor. Minor trauma and emotional stress are the most common initiating events leading to contact system activation and excessive uncontrolled bradykinin release. This manifests as angioedema, a vascular reaction of the deeper layers of the skin and mucous membranes, with vasodilatation and increased permeability resulting in tissue swelling. Severe angioedema can occur in the perioperative period, leading to fatal airway obstruction. We describe the anaesthetic management of a child with HAE for dental rehabilitation and provide an review of the relevant literature.

Publication details

DOI
10.18295/2075-0528.1509
Journal
Sultan Qaboos University Medical Journal, 13(3), 467-471
Publisher
Sultan Qaboos University
Open access
Gold open access
License
CC BY-ND 4.0

Cite this article

APA 7

Narayanan, A., Date, R. R., Bhakta, S., Pradipta, & Srinivasan, S. (2025). Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor: Case report and literature review. Sultan Qaboos University Medical Journal, 13(3), 467-471. https://doi.org/10.18295/2075-0528.1509

MLA 9

Narayanan, Aravind, et al. "Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor: Case report and literature review." Sultan Qaboos University Medical Journal, vol. 13, no. 3, 2025, pp. 467-471. https://doi.org/10.18295/2075-0528.1509.

Chicago (author–date)

Narayanan, Aravind, Rohit R. Date, Sanathkumar Bhakta, Pradipta, and Sinnakirouchenane Srinivasan. 2025. "Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor: Case report and literature review." Sultan Qaboos University Medical Journal 13 (3): 467-471. https://doi.org/10.18295/2075-0528.1509.

Harvard

Narayanan, A., Date, R. R., Bhakta, S., Pradipta and Srinivasan, S. (2025) 'Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor: Case report and literature review', Sultan Qaboos University Medical Journal, 13(3), pp. 467-471. doi:10.18295/2075-0528.1509.

Vancouver

Narayanan A, Date RR, Bhakta S, Pradipta, Srinivasan S. Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor: Case report and literature review. Sultan Qaboos University Medical Journal. 2025;13(3):467-471. doi:10.18295/2075-0528.1509

IEEE

A. Narayanan, R. R. Date, S. Bhakta, Pradipta, and S. Srinivasan, "Anaesthesia Management of a Patient with Hereditary Angioedema with Prophylactic Administration of C1 Esterase Inhibitor: Case report and literature review," Sultan Qaboos University Medical Journal, vol. 13, no. 3, pp. 467-471, 2025, doi: 10.18295/2075-0528.1509.