Abstract
Choriocarcinoma (CC) is a malignant neoplasm of the trophoblastic tissue, with a potential to metastasise to distant organs. Limited case of gestational CC develops after a long latent period. We report a 52-year-old postmenopausal woman who developed metastatic choriocarcinoma presumably of gestational origin, 8 years after the last pregnancy and 2 years after the last menstrual period. The patient was brought to the emergency room of a tertiary care centre in Muscat, Oman, in 2022 and was diagnosed with CC metastatic to the brain, spleen, lung and the kidney. The β-human chorionic gonadotrophin level was found to be raised (1,292,867 mIU/mL). The International Federation of Gynecologic Oncology risk score was calculated to be 14 (very high risk). The patient was initially treated with whole-brain radiotherapy and splenic artery embolisation because of a hemoperitoneum. Afterwards the patient received systemic treatment using the standard EMA/CO regimen till complete serological remission. Keywords: Choriocarcinoma; Postmenopause; Latency Period; Brain; Oman.
Publication details
- DOI
- 10.18295/squmj.5.2023.036
- Journal
- Sultan Qaboos University Medical Journal, 24(1), 135-138
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Zribi, A., Al Mazroui, R., Sayani, R., & Burney, I. A. (2025). An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report. Sultan Qaboos University Medical Journal, 24(1), 135-138. https://doi.org/10.18295/squmj.5.2023.036
MLA 9
Zribi, Aref, et al. "An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report." Sultan Qaboos University Medical Journal, vol. 24, no. 1, 2025, pp. 135-138. https://doi.org/10.18295/squmj.5.2023.036.
Chicago (author–date)
Zribi, Aref, Reem Al Mazroui, Raza Sayani, and Ikram A. Burney. 2025. "An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report." Sultan Qaboos University Medical Journal 24 (1): 135-138. https://doi.org/10.18295/squmj.5.2023.036.
Harvard
Zribi, A., Al Mazroui, R., Sayani, R. and Burney, I. A. (2025) 'An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report', Sultan Qaboos University Medical Journal, 24(1), pp. 135-138. doi:10.18295/squmj.5.2023.036.
Vancouver
Zribi A, Al Mazroui R, Sayani R, Burney IA. An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report. Sultan Qaboos University Medical Journal. 2025;24(1):135-138. doi:10.18295/squmj.5.2023.036
IEEE
A. Zribi, R. Al Mazroui, R. Sayani, and I. A. Burney, "An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report," Sultan Qaboos University Medical Journal, vol. 24, no. 1, pp. 135-138, 2025, doi: 10.18295/squmj.5.2023.036.