[
    {
        "id": "osp-10076",
        "type": "article-journal",
        "title": "An Unusual Presentation of Choriocarcinoma in a Postmenopausal Woman: A case report",
        "author": [
            {
                "family": "Zribi",
                "given": "Aref"
            },
            {
                "family": "Al Mazroui",
                "given": "Reem"
            },
            {
                "family": "Sayani",
                "given": "Raza"
            },
            {
                "family": "Burney",
                "given": "Ikram A."
            }
        ],
        "URL": "https://omanscience.com/en/articles/an-unusual-presentation-of-choriocarcinoma-in-a-postmenopausal-woman-a-case-report",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "24",
        "issue": "1",
        "page": "135-138",
        "DOI": "10.18295/squmj.5.2023.036",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Choriocarcinoma (CC) is a malignant neoplasm of the trophoblastic tissue, with a potential to metastasise to distant organs. Limited case of gestational CC develops after a long latent period. We report a 52-year-old postmenopausal woman who developed metastatic choriocarcinoma presumably of gestational origin, 8 years after the last pregnancy and 2 years after the last menstrual period. The patient was brought to the emergency room of a tertiary care centre in Muscat, Oman, in 2022 and was diagnosed with CC metastatic to the brain, spleen, lung and the kidney. The β-human chorionic gonadotrophin level was found to be raised (1,292,867 mIU/mL). The International Federation of Gynecologic Oncology risk score was calculated to be 14 (very high risk). The patient was initially treated with whole-brain radiotherapy and splenic artery embolisation because of a hemoperitoneum. Afterwards the patient received systemic treatment using the standard EMA/CO regimen till complete serological remission.\n\nKeywords: Choriocarcinoma; Postmenopause; Latency Period; Brain; Oman."
    }
]