Abstract
Background: The aim of the study was to assess the midterm efficacy and safety of the iStent glaucoma device in patients with open-angle glaucoma (OAG). Materials and methods: We conducted a retrospective case series of all patients implanted with iStent inject® in OAG. Primary outcomes included intraocular pressure (IOP) and the reduction of antiglaucoma medications. Safety outcomes comprised adverse complications, additional surgeries, and postoperative best-corrected visual acuity (BCVA). Results: Eight eyes from eight patients were included in this series. The mean age was 56.3 ± 17.5 years. Six eyes had primary OAG and two eyes had secondary OAG. The majority of eyes (75%) had mild-to-moderate glaucoma. Five eyes underwent combined surgery, whereas the remaining three eyes underwent a standalone procedure. The mean baseline IOP was 22.9 ± 8.2 mmHg, and the mean IOP at 2 years after the procedure was 13.6 ± 2.8 mmHg. There was a 44.5% (10.2 ± 2.5 mmHg; P = 0.002) IOP reduction over 2 years. There was also a reduction in medication burden from a baseline mean of 3.4 ± 0.7 to 2.0 ± 1.2 (P = 0.17). There was no documented intraoperative adverse complication, whereas one patient required trabeculectomy post iStent for IOP control. Conclusion: iStent inject implantation safely reduced IOP and medication burden up to 24 months postoperative.
Keywords
Publication details
- DOI
- 10.4103/ojo.ojo_223_23
- Journal
- Oman Journal of Ophthalmology, 18(1), 28-32
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Teoh, R. J. J., Yogesvaran, R., Cheng, F. F. Y., & Muji, R. (2025). A 2-year longitudinal evaluation of the iStent inject® system for open-angle glaucoma in East Asian eyes. Oman Journal of Ophthalmology, 18(1), 28-32. https://doi.org/10.4103/ojo.ojo_223_23
MLA 9
Teoh, Ru Jian Jonathan, et al. "A 2-year longitudinal evaluation of the iStent inject® system for open-angle glaucoma in East Asian eyes." Oman Journal of Ophthalmology, vol. 18, no. 1, 2025, pp. 28-32. https://doi.org/10.4103/ojo.ojo_223_23.
Chicago (author–date)
Teoh, Ru Jian Jonathan, Rupini Yogesvaran, Felicia Foo Yuen Cheng, and Roslinah Muji. 2025. "A 2-year longitudinal evaluation of the iStent inject® system for open-angle glaucoma in East Asian eyes." Oman Journal of Ophthalmology 18 (1): 28-32. https://doi.org/10.4103/ojo.ojo_223_23.
Harvard
Teoh, R. J. J., Yogesvaran, R., Cheng, F. F. Y. and Muji, R. (2025) 'A 2-year longitudinal evaluation of the iStent inject® system for open-angle glaucoma in East Asian eyes', Oman Journal of Ophthalmology, 18(1), pp. 28-32. doi:10.4103/ojo.ojo_223_23.
Vancouver
Teoh RJJ, Yogesvaran R, Cheng FFY, Muji R. A 2-year longitudinal evaluation of the iStent inject® system for open-angle glaucoma in East Asian eyes. Oman Journal of Ophthalmology. 2025;18(1):28-32. doi:10.4103/ojo.ojo_223_23
IEEE
R. J. J. Teoh, R. Yogesvaran, F. F. Y. Cheng, and R. Muji, "A 2-year longitudinal evaluation of the iStent inject® system for open-angle glaucoma in East Asian eyes," Oman Journal of Ophthalmology, vol. 18, no. 1, pp. 28-32, 2025, doi: 10.4103/ojo.ojo_223_23.