نسخة أولية وصول مفتوح
Establishing ordinary differential equations (ODEs) describing population data is a fundamental part of mathematical modeling in pharmacology, crucial to developing digital twins. However, doing so from sparse, noisy data is a slow, expert-driven task. Existing automated methods either search a restricted model space o …
نسخة أولية وصول مفتوح
On-policy learning has been argued to reduce catastrophic forgetting, produce sparser parameter updates, and improve generalisation. However, existing comparisons between supervised fine-tuning and reinforcement learning vary many factors simultaneously, making the contribution of rollout policy difficult to isolate. W …
نسخة أولية وصول مفتوح
Electronic health records provide irregular observations of latent patient states that evolve continuously over time. Recent autoregressive models condition on clinical histories to forecast future events as sequences of discrete observations. Conversely, multi-marginal flow matching provides a continuous-time formulat …