Automated research systems increasingly run LLM agents over long horizons, but more inference does not by itself produce more progress: agents replay growing histories, duplicate one another's work, or stop experimenting while token consumption continues. Yet most evaluations use short budgets or benchmarks that satura …
What makes great scientists great? Even as AI systems start to make progress on open problems, scientists remain far ahead of them at sensing which prior idea, buried in an ever-growing archive of research, a new problem needs. To study this skill, we draw on researchers who know firsthand which earlier work advanced t …
Single-cell RNA-seq representation learning is fundamentally label-free: cell identities, states, and contexts are not fixed training targets, so what constitutes signal or nuisance is analysis-dependent. A single representation must therefore preserve biological identity and state, remain robust to nuisance context, a …
An LLM agent's capability is largely magnified by its harness, namely the prompts, control flow, tooling, memory, and context management surrounding the frozen backbone model. Recent methods increasingly automate this process by iteratively proposing and selecting component-wise edits of an agent harness, practically e …