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Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated diarrhea; however, its association with antituberculous therapy (ATT) remains underrecognized. This review examines the risk, mechanisms, and clinical implications of CDI in patients with active tuberculosis (TB). Although ATT is tra …
Urinary tract infections (UTIs) are commonly caused by bacteria that enter through the urethra and multiply in the bladder. The rising antibiotic resistance makes bacterial infections increasingly difficult to treat, necessitating the development of alternative solutions to combat resistant bacteria. The World Health O …
Colorectal cancer (CRC) presents high incidence and mortality, largely due to late diagnosis and the persistence of cancer stem cells (CSCs), which contribute to chemoresistance and poor patient outcomes. TRAIL (TNF-related apoptosis-inducing ligand) is considered a promising therapeutic agent because of its ability to …
Background: Wrist involvement in juvenile idiopathic arthritis (JIA) is associated with a more aggressive disease course and poorer long-term outcomes. However, data integrating imaging findings, treatment decisions, and procedural outcomes remains limited. Methods: We conducted a single-center retrospective cohort stu …
Background: Myeloproliferative neoplasms (MPNs)—including primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocythemia (ET)—are clonal stem-cell disorders driven by JAK–STAT pathway activation within an inflammatory microenvironment. Ruxolitinib (RUX), a JAK1/2 inhibitor, improves splenomegaly and …
Background: Assisted Partner Notification Services (APNS) support HIV disclosure and reduce HIV transmission. Despite this potential, APNS remains underutilized due to several barriers. A clearer understanding of APNS utilization, barriers, and the facilitators is essential to guide APNS improvement. Objectives: This s …
Traumatic intracranial aneurysms are rare consequences of blunt or penetrating head injury, carrying significant morbidity and mortality. We report a 33-year-old male who sustained severe head trauma with base of skull fracture and subarachnoid hemorrhage following a motor vehicle accident. He underwent craniotomy with …
Prediabetes is a critical precursor to type 2 diabetes (T2DM) and cardiometabolic diseases, yet its burden in Oman remains understudied. Leveraging data from Oman’s 2023 National Screening Program, this study quantifies the prevalence of prediabetes and its risk profiles among adults in Muscat Governorate—providing urg …
Central nervous system (CNS) tumors in children, though uncommon, pose distinct challenges due to their unique pathological and clinical features, which often differ from adult cases. Effective management of pediatric CNS tumors can be complicated, with complete surgical resection remaining a critical goal, in conditio …
Background: Neck and shoulder pain are prevalent occupational health issues among school teachers globally, impacting work performance and quality of life. This study aimed to assess the prevalence and factors associated with neck and shoulder pain among school teachers in Oman. Methods: A cross-sectional study using c …