Reconstructing physical fields from training samples that are always incomplete requires learning spatial structure from fragmented observations. Existing context--query work establishes how held-out observations provide valid training targets, but this does not make the complete-field distribution identifiable when ev …
Large language models offer a promising foundation for chemical reasoning, bringing together chemical knowledge and multistep problem solving. Chemical intuition can provide an initial sense of plausible outcomes before the details of a solution are fully worked out. Inspired by how such expectations complement explici …
Single-step retrosynthesis models are commonly evaluated by their ability to recover recorded reactions. In practice, chemists may need to choose among several precursor sets for the same product, for example to preserve a particular motif. Recovering a recorded answer alone does not establish this ability to follow a …
Retrosynthesis enables the discovery of viable synthetic routes to target molecules. It plays a central role in modern drug discovery and materials design. Retrosynthesis involves molecular graph transformations that can change both connectivity and graph size. These transformations may introduce reactant components ab …
Large language models are increasingly expected to support diverse chemical reasoning capabilities within a unified model. One approach is to develop specialized capabilities separately and consolidate them through multi-teacher on-policy distillation, but this raises two questions: how should specialization be organiz …