Review article Open access
Vascular endothelial growth factor trap-eye and trap technology: Aflibercept from bench to bedside
… i-vascular endothelial growth factor (VEGF) currently used to treat eye diseases have included monoclonal antibodies, antibody fragments, and an aptamer. A different method of achieving VEGF blockade in retinal diseases includes the concept of a cytokine trap. Cytokine traps technology are being evaluated for the treat …