Scientific articles

Diagnosis and Genetic Analysis of Glutaric Acidaemia Type I: Very rarely seen inborn error of metabolism

Genetic Analysis and Clinical Effect of ACE2 Gene Variants (rs2285666 and rs4646188) on Coronary Syndrome in Dyslipidaemia Patients

Objectives: This study aimed to investigate the association of two intronic polymorphisms of the ACE2 gene (rs2285666 and rs4646188) with coronary artery disease (CAD) in Iraqi patients with dyslipidaemia. Methods: This case-control study was conducted from March to September 2023 at the Iraqi Center of Heart Disease, …

Genetic Diversity Analysis of Methicillin-resistant Staphylococcus aureus Strains Isolated from Intensive Care Unit in Iran

Objectives: Staphylococcus aureus has emerged as a major public health concern. It is a common pathogen in high-risk hospital intensive care units (ICUs). We analyzed the molecular characteristics on the SCCmec and spa genes of S. aureus isolates gathered from ICUs. The antibiotic resistance patterns and carriage of re …

Association of FTO rs9939609 SNP with Obesity and Obesity- Associated Phenotypes in a North Indian Population

… disorder that has a significant impact on morbidity and mortality. Twin and adoption studies support the genetic influence on variation of obesity, and the estimates of the heritability of body mass index (BMI) is significantly high (30 to 70%). Variants in the fat mass and obesity-associated (FTO) gene have been asso …

Risk Factors of Nonsteroidal Anti-inflammatory Drug-exacerbated Respiratory Disease: A Systematic Review and Meta-analysis of Observational Studies

Objectives: This meta-analysis aimed to identify the risk factors associated with nonsteroidal anti-inflammatory drug -exacerbated respiratory disease (NERD), a chronic eosinophilic, inflammatory respiratory disorder characterized by hypersensitivity to aspirin or nonsteroidal anti-inflammatory drugs in patients with a …

Successful Management by Selective Embryo in the Carnitine-acylcarnitine Translocase Deficiency with SLC25A20 C.199-10T>G Variation: The First Case Report from Vietnam and Literature Review

… iation is a rare condition, typically associated with severe neonatal outcomes. Recently, preimplantation genetic testing (PGT) has emerged as a screening test applicable to embryos produced through in vitro fertilization for genetic analysis before transfer. Thus, PGT allows for the identification and elimination of e …

Advances and Challenges in the Fitness Dependent Optimizer: A Systematic Survey (2019–2026)

… s a quantitative comparison of FDO with three classical metaheuristics Particle Swarm Optimization (PSO), Genetic Algorithm (GA) and Artificial Bee Colony (ABC) for convergence behavior, and exploration and exploitation balance; fifthly, it points out priority research gaps. The most decisive finding of this study is t …

Potential of Microsatellite Markers for Genetic Assessment of Scalloped Spiny Lobster (Panulirus homarus) Populations in Al Sharqiyah Governorate and their Application in Specie’s Fishery Management

… loitation and adaptation, therefore different stocks need different conservation plan. In this study, the genetic diversity and population differentiation of 50 P. homarus (the most present spiny lobster subspecies in Oman) from two regions (Al-Ashkharah and Masirah) of Al Sharqyah governorate were studied using 49 mic …

Potential of Microsatellite Markers for Genetic Assessment of Scalloped Spiny Lobster (Panulirus homarus) Populations in Al Sharqiyah Governorate and their Application in Specie’s Fishery Management

… loitation and adaptation, therefore different stocks need different conservation plan. In this study, the genetic diversity and population differentiation of 50 P. homarus (the most present spiny lobster subspecies in Oman) from two regions (Al-Ashkharah and Masirah) of Al Sharqyah governorate were studied using 49 mic …

Evaluation of Potato Cultivars Grown in Saudi Arabia by Morphological Characters and RAPD Markers

Genetic diversity of 10 potato cultivars was investigated at the DNA level with the random amplified polymorphic DNA (RAPD) procedure and at the phenotypic level using morphological characters. The results indicated that there were considerable variations among the different studied cultivars. Cultivars Victoria, Frizi …

Marine biotechnology: Emerging opportunities and future perspectives

The rapid growth of genetic, cellular and molecular technologies is enabling scientists to explore and develop marine resources for widespread applications in the food, medical, pharmaceutical, environmental and energy industries. Marine biotechnology products and services were estimated at 2.8 billion euros in 2010, w …

Characterization of Genetic Diversity in Dhofari Wild Gazelles

… Recently, gazelles’ populations have been facing reduction in the numbers. Consequently, gradual loss of genetic diversity is inevitable. This loss is considered one of the main threats that attribute to a loss of habitat and may lead to gazelle extinction. Till now, little is known about the status of the genetic div …