OSP Index

Scientific articles

6 results

Research article Open access

Elastosis in Breast Cancer as a Surrogate Marker for Estrogen Receptor Positivity

Samah Al Abri, Abdulhakeem Al-Rawahi, Lakshmi Rao · Oman Medical Journal · 2021 · 10.5001/omj.2021.60

… g semi-quantitative methods. We also sought to investigate the relationship between stromal elastosis and estrogen receptor (ER), progesterone receptor (PR), HER2/neu receptor tumor grade, and Ki-67 index. Furthermore, we evaluated the diagnostic accuracy of hematoxylin and eosin (H&E) stain method in quantifying elast …

Research article Open access

Immunohistochemical Expression of Estrogen and Progesterone Receptors in Human Colorectal Adenoma and Carcinoma Using Specified Automated Cellular Image Analysis System: A Clinicopathological Study

Ban Jumaa Qasim, Hussam Hasson Ali, Alaa Ghani Hussein · Oman Medical Journal · 2011 · 10.5001/omj.2011.78

Objectives: To evaluate the immunohistochemical expression of estrogen receptors (ER) and progesterone receptors (PR) in colorectal adenoma and adenocarcinoma and to correlate this immunohistochemical expression with different clinicopathological parameters. Methods: The study was retrospectively designed. A total of 8 …

Research article Open access

A case report on letrozole-related maculopathy

Sitara Azeem, Ahmed Al-Hinai, Nadiya Al Kharousi et al. · Oman Journal of Ophthalmology · 2023 · 10.4103/ojo.ojo_269_22

Letrozole is an oral aromatase inhibitor used in the treatment of hormone receptor-positive breast cancers in postmenopausal women. It acts by inhibiting the conversion of androgens to estrogen thereby lowering the estrogen synthesis in the body. We report a case of bilateral cystoid macular edema (CME) in a postmenopa …

Research article Open access

Meningioma Prognostic Tool Based on Correlation of Histopathological Grading and Immunohistochemistry

Mahak Shafat, Nayil Khursheed, Nazia Walvir et al. · Oman Medical Journal · 2024 · 10.5001/omj.2024.56

… re simple, they do not always correlate with patient outcomes. This study aimed to evaluate the status of estrogen receptor (ER), progesterone receptor (PR), and proliferation marker Ki-67/molecular immunology borstel-1 (MIB-1) in the three grades of meningioma. Methods: We evaluated the data of meningioma patients who …

Research article Open access

Immunohistochemical and Clinicopathological Characteristics of Invasive Breast Carcinoma in Nigeria

Rasheed Mumini Wemimo, Uchechukwu Brian Eziagu, Olayide Agodirin Sulaiman et al. · Oman Medical Journal · 2023 · 10.5001/omj.2023.101

… he most common lymph node involvement was N1 (56.6%). Immunohistochemical assessment of these tumors with estrogen receptor, progesterone receptor, and human epidermal growth factor receptor-2 (HER-2) biomarkers expressed positivity of 36.3%, 28.3%, and 41.6%, respectively. These tumors were immunohistochemically class …

Research article Open access

Differential Expression of Androgen Receptor in Type I and Type II Endometrial Carcinomas: A Clinicopathological Analysis and Correlation with Outcome

Nisreen Abu Shahin, Tariq Aladily, Nezeen Abu Alhaj et al. · Oman Medical Journal · 2021 · 10.5001/omj.2021.53

… stic considerations. Female hormone expression in EC is extensively studied; however, data about androgen receptor (AR) expression in EC are sparse. We aimed to study AR expression in different types of EC at our institute and whether it had an impact on patient outcomes. Methods: A retrospective analysis of EC cases d …

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