Abstract
We report the case of a 57-year-old male physician who presented with a life threatening secretory and refractory diarrhoea of around 20 L/day. This was complicated by severe hypotension, hypokalaemia, hypercalcaemia, renal failure requiring dialysis, metabolic acidosis, cardiorespiratory arrest and ventilation for 12 days. His diarrhoea responded immediately to the first dose of a therapeutic trial of subcutaneous octreotide 100 mcg 8 hourly which was started on clinical grounds alone before any investigations were carried out. After one day he was extubated and his blood pressure returned to normal. When a functioning neuroendocrine tumour is suspected clinically, the use of octreotide can, as in this case, be life saving.
Publication details
- DOI
- 10.18295/2075-0528.1245
- Journal
- Sultan Qaboos University Medical Journal, 11(1), 104-107
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Elshafie, O., Grant, C., Jain, A., Rajeev, & Woodhouse, N. (2025). VIPoma Crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide. Sultan Qaboos University Medical Journal, 11(1), 104-107. https://doi.org/10.18295/2075-0528.1245
MLA 9
Elshafie, Omayma, et al. "VIPoma Crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide." Sultan Qaboos University Medical Journal, vol. 11, no. 1, 2025, pp. 104-107. https://doi.org/10.18295/2075-0528.1245.
Chicago (author–date)
Elshafie, Omayma, Christopher Grant, Aisha Jain, Rajeev, and Nicholas Woodhouse. 2025. "VIPoma Crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide." Sultan Qaboos University Medical Journal 11 (1): 104-107. https://doi.org/10.18295/2075-0528.1245.
Harvard
Elshafie, O., Grant, C., Jain, A., Rajeev and Woodhouse, N. (2025) 'VIPoma Crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide', Sultan Qaboos University Medical Journal, 11(1), pp. 104-107. doi:10.18295/2075-0528.1245.
Vancouver
Elshafie O, Grant C, Jain A, Rajeev, Woodhouse N. VIPoma Crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide. Sultan Qaboos University Medical Journal. 2025;11(1):104-107. doi:10.18295/2075-0528.1245
IEEE
O. Elshafie, C. Grant, A. Jain, Rajeev, and N. Woodhouse, "VIPoma Crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide," Sultan Qaboos University Medical Journal, vol. 11, no. 1, pp. 104-107, 2025, doi: 10.18295/2075-0528.1245.