Abstract

Topiramate is a sulfamate-substituted monosaccharide used in the treatment of seizures, and prophylaxis of migraine. A number of ocular side-effects have been described with use of topiramate, like bilateral angle closure, acute myopia and macular striae. Ultrasound biomicroscopy (UBM) clinches the diagnosis after ruling out other causes of shallow anterior chamber. Previous studies have not demonstrated internal limiting membrane folds presenting as macular striae. We report a case of topiramate-induced acute myopia with angle closure and macular striae in a young adult. This is the first report wherein striae formation after low doses of topiramate and their resolution have been documented by Optical Coherence Tomography (OCT).

Keywords

Publication details

DOI
10.4103/0974-620x.60018
Journal
Oman Journal of Ophthalmology, 3(1), 26-28
Publisher
Medknow Publications
Open access
Gold open access

Cite this article

APA 7

Natesh, S., Rajashekhara, S. K., Rao, A. S. D., & Shetty, B. (2010). Topiramate-induced angle closure with acute myopia, macular striae. Oman Journal of Ophthalmology, 3(1), 26-28. https://doi.org/10.4103/0974-620x.60018

MLA 9

Natesh, S, et al. "Topiramate-induced angle closure with acute myopia, macular striae." Oman Journal of Ophthalmology, vol. 3, no. 1, 2010, pp. 26-28. https://doi.org/10.4103/0974-620x.60018.

Chicago (author–date)

Natesh, S, S K Rajashekhara, A S D Rao, and B Shetty. 2010. "Topiramate-induced angle closure with acute myopia, macular striae." Oman Journal of Ophthalmology 3 (1): 26-28. https://doi.org/10.4103/0974-620x.60018.

Harvard

Natesh, S., Rajashekhara, S. K., Rao, A. S. D. and Shetty, B. (2010) 'Topiramate-induced angle closure with acute myopia, macular striae', Oman Journal of Ophthalmology, 3(1), pp. 26-28. doi:10.4103/0974-620x.60018.

Vancouver

Natesh S, Rajashekhara SK, Rao ASD, Shetty B. Topiramate-induced angle closure with acute myopia, macular striae. Oman Journal of Ophthalmology. 2010;3(1):26-28. doi:10.4103/0974-620x.60018

IEEE

S. Natesh, S. K. Rajashekhara, A. S. D. Rao, and B. Shetty, "Topiramate-induced angle closure with acute myopia, macular striae," Oman Journal of Ophthalmology, vol. 3, no. 1, pp. 26-28, 2010, doi: 10.4103/0974-620x.60018.