Abstract
BACKGROUND: Acne vulgaris (AV) is one of the most common skin diseases with major psychological impacts. Hence, selecting the best treatment modality is so important; there are different ways to treat AV such as topical and systemic agents, laser, and also photodynamic therapy. In this study, we tried to assess the difference between the efficacy of combination therapy with intense pulsed light (IPL) and benzoyl peroxide (BPO) in comparison with IPL and adapalene (AD) in the treatment of the mild to moderate AV. MATERIALS AND METHODS: Thirty Iranian females in reproductive age with mild to moderate acne were enrolled in this study. The left and right side of the patients were randomized to receive either AD 0.1% or BPO 5% every other day plus three sessions of monthly apart IPL in the treatment of AV. Different parameters of AV such as acne severity index (ASI), total acne lesions counting (TLC), and Acne Global Severity Scale (AGSS) were measured before, during, and after the treatments. RESULTS: > 0.05). No significant side effects were observed in both groups. CONCLUSION: Our study shows that there was not any significant difference between combining IPL with either AD or BPO so we can use either one of these combinations to achieve similar efficacy.
Keywords
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Publication details
- DOI
- 10.4103/jrms.jrms_398_19
- Journal
- Journal of Research in Medical Sciences, 24(1), 101
- Publisher
- Wolters Kluwer Medknow Publications
- Open access
- Gold open access
- License
- CC BY-NC-SA 4.0
Cite this article
APA 7
Mokhtari, F., Shajari, A., Iraji, F., Faghihi, G., Siadat, A. H., Sadeghian, G., & Adibi, N. (2019). The effectiveness of adapalene 0.1% with intense pulsed light versus benzoyl peroxide 5% with intense pulsed light in the treatment of acne vulgaris: A comparative study. Journal of Research in Medical Sciences, 24(1), 101. https://doi.org/10.4103/jrms.jrms_398_19
MLA 9
Mokhtari, Fatemeh, et al. "The effectiveness of adapalene 0.1% with intense pulsed light versus benzoyl peroxide 5% with intense pulsed light in the treatment of acne vulgaris: A comparative study." Journal of Research in Medical Sciences, vol. 24, no. 1, 2019, pp. 101. https://doi.org/10.4103/jrms.jrms_398_19.
Chicago (author–date)
Mokhtari, Fatemeh, Atefeh Shajari, Fariba Iraji, Gita Faghihi, Amir Hossein Siadat, Giti Sadeghian, and Neda Adibi. 2019. "The effectiveness of adapalene 0.1% with intense pulsed light versus benzoyl peroxide 5% with intense pulsed light in the treatment of acne vulgaris: A comparative study." Journal of Research in Medical Sciences 24 (1): 101. https://doi.org/10.4103/jrms.jrms_398_19.
Harvard
Mokhtari, F., Shajari, A., Iraji, F., Faghihi, G., Siadat, A. H., Sadeghian, G. and Adibi, N. (2019) 'The effectiveness of adapalene 0.1% with intense pulsed light versus benzoyl peroxide 5% with intense pulsed light in the treatment of acne vulgaris: A comparative study', Journal of Research in Medical Sciences, 24(1), pp. 101. doi:10.4103/jrms.jrms_398_19.
Vancouver
Mokhtari F, Shajari A, Iraji F, Faghihi G, Siadat AH, Sadeghian G, et al. The effectiveness of adapalene 0.1% with intense pulsed light versus benzoyl peroxide 5% with intense pulsed light in the treatment of acne vulgaris: A comparative study. Journal of Research in Medical Sciences. 2019;24(1):101. doi:10.4103/jrms.jrms_398_19
IEEE
F. Mokhtari, A. Shajari, F. Iraji, G. Faghihi, A. H. Siadat, G. Sadeghian, and N. Adibi, "The effectiveness of adapalene 0.1% with intense pulsed light versus benzoyl peroxide 5% with intense pulsed light in the treatment of acne vulgaris: A comparative study," Journal of Research in Medical Sciences, vol. 24, no. 1, pp. 101, 2019, doi: 10.4103/jrms.jrms_398_19.