Abstract
The denervation or activation of the sympathetic nerve in the kidney can affect renal hemodynamics. The sympathetic nervous system regulates the physiological functions of the kidneys. Stimulation of sympathetic efferent nerves affects various parameters related to renal hemodynamics, including sodium excretion, renin secretion, and renal blood flow (RBF). Hence, renal sympathetic fibers may also play an essential role in regulating systemic vascular resistance and controlling blood pressure. In the absence of renal nerves, the hemodynamics response to stimuli is negligible or absent. The effect of renal sympathetic denervation on RBF is dependent on several factors such as interspecies differences, the basic level of nerve activity in the vessels or local density of adrenergic receptor in the vascular bed. The role of renal denervation has been investigated therapeutically in hypertension and related disorders. Hence, the dynamic impact of renal nerves on RBF enables using RBF dynamic criteria as a marker for renal denervation therapy.
Keywords
Subject
Publication details
- DOI
- 10.4103/jrms.jrms_216_23
- Journal
- Journal of Research in Medical Sciences, 28(1), 76
- Publisher
- Wolters Kluwer Medknow Publications
- Open access
- Gold open access
- License
- CC BY-NC-SA 4.0
Cite this article
APA 7
Kharazmi, F., Dastgerdi, H. H., Pourshanazari, A., & Nematbakhsh, M. (2023). The denervation or activation of renal sympathetic nerve and renal blood flow. Journal of Research in Medical Sciences, 28(1), 76. https://doi.org/10.4103/jrms.jrms_216_23
MLA 9
Kharazmi, Fatemeh, et al. "The denervation or activation of renal sympathetic nerve and renal blood flow." Journal of Research in Medical Sciences, vol. 28, no. 1, 2023, pp. 76. https://doi.org/10.4103/jrms.jrms_216_23.
Chicago (author–date)
Kharazmi, Fatemeh, Hajaralsadat Hosseini Dastgerdi, Aliasghar Pourshanazari, and Mehdi Nematbakhsh. 2023. "The denervation or activation of renal sympathetic nerve and renal blood flow." Journal of Research in Medical Sciences 28 (1): 76. https://doi.org/10.4103/jrms.jrms_216_23.
Harvard
Kharazmi, F., Dastgerdi, H. H., Pourshanazari, A. and Nematbakhsh, M. (2023) 'The denervation or activation of renal sympathetic nerve and renal blood flow', Journal of Research in Medical Sciences, 28(1), pp. 76. doi:10.4103/jrms.jrms_216_23.
Vancouver
Kharazmi F, Dastgerdi HH, Pourshanazari A, Nematbakhsh M. The denervation or activation of renal sympathetic nerve and renal blood flow. Journal of Research in Medical Sciences. 2023;28(1):76. doi:10.4103/jrms.jrms_216_23
IEEE
F. Kharazmi, H. H. Dastgerdi, A. Pourshanazari, and M. Nematbakhsh, "The denervation or activation of renal sympathetic nerve and renal blood flow," Journal of Research in Medical Sciences, vol. 28, no. 1, pp. 76, 2023, doi: 10.4103/jrms.jrms_216_23.