Abstract
Crescentic glomerulonephritis has been associated with several solid tumour malignancies. Only a few cases of nephropathy have been reported in association with tubo-ovarian/peritoneal malignancies. We report a 55-year-old female patient who presented to a tertiary care centre, Muscat, Oman, in 2022. She developed combined immune complex-mediated glomerulonephritis and pauci-immune necrotising crescentic vasculitis simultaneously with the diagnosis of tubo-ovarian/peritoneal cancer. The baseline estimated glomerular filtration rate (eGFR) was 13 mL/min. The patient received two doses of rituximab and three doses of pulse corticosteroids, leading to significant improvement in renal function and the disappearance of her proteinuria. The eGFR improved to >60mL/min; her proteinuria gradually resolved after 10 weeks of treatment. She was then given a combination chemotherapy treatment for tubo-ovarian/peritoneal cancer leading to a normalisation of her CA-125 after three months of therapy. Keywords: Peritoneal Neoplasm; Glomerulonephritis; Vasculitis; Chemotherapy; Case Report; Oman.
Publication details
- DOI
- 10.18295/squmj.1.2023.013
- Journal
- Sultan Qaboos University Medical Journal, 24(1), 119-122
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Zribi, A., Nagy, A., Al Riyami, M., & Burney, I. A. (2025). Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report. Sultan Qaboos University Medical Journal, 24(1), 119-122. https://doi.org/10.18295/squmj.1.2023.013
MLA 9
Zribi, Aref, et al. "Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report." Sultan Qaboos University Medical Journal, vol. 24, no. 1, 2025, pp. 119-122. https://doi.org/10.18295/squmj.1.2023.013.
Chicago (author–date)
Zribi, Aref, Amro Nagy, Marwa Al Riyami, and Ikram A. Burney. 2025. "Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report." Sultan Qaboos University Medical Journal 24 (1): 119-122. https://doi.org/10.18295/squmj.1.2023.013.
Harvard
Zribi, A., Nagy, A., Al Riyami, M. and Burney, I. A. (2025) 'Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report', Sultan Qaboos University Medical Journal, 24(1), pp. 119-122. doi:10.18295/squmj.1.2023.013.
Vancouver
Zribi A, Nagy A, Al Riyami M, Burney IA. Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report. Sultan Qaboos University Medical Journal. 2025;24(1):119-122. doi:10.18295/squmj.1.2023.013
IEEE
A. Zribi, A. Nagy, M. Al Riyami, and I. A. Burney, "Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report," Sultan Qaboos University Medical Journal, vol. 24, no. 1, pp. 119-122, 2025, doi: 10.18295/squmj.1.2023.013.