Abstract
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited condition characterized by the growth of multiple bilateral cysts in the kidneys. We describe the case of a 35-year-old male with combined ADPKD and type 1 diabetes mellitus with a strong family history of both. At the age of 32, he developed end-stage kidney disease for which he underwent preemptive simultaneous pancreatic and kidney transplant, which in turn led to multiple perioperative complications. Evaluation of familial clustering of genetic disease is critical in genetic epidemiology and precision medicine as it enables estimation of lifetime disease risk and early assessment as well as detection of the disease among one’s siblings.
Keywords
Subject
Publication details
- DOI
- 10.5001/omj.2024.18
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Al Alawi, I., Mohammed, E., Al Rahbi, F., Metry, A., Hannawi, S., & Al Salmi, I. (2024). Simultaneous Pancreatic and Kidney Transplant in Adult with Autosomal Dominant Polycystic Kidney Disease and Type I Diabetes Mellitus: Post Surgical Events and Genetic Review. Oman Medical Journal. https://doi.org/10.5001/omj.2024.18
MLA 9
Al Alawi, Intisar, et al. "Simultaneous Pancreatic and Kidney Transplant in Adult with Autosomal Dominant Polycystic Kidney Disease and Type I Diabetes Mellitus: Post Surgical Events and Genetic Review." Oman Medical Journal, 2024. https://doi.org/10.5001/omj.2024.18.
Chicago (author–date)
Al Alawi, Intisar, Ehab Mohammed, Fatma Al Rahbi, AbdelMasieh Metry, Suad Hannawi, and Issa Al Salmi. 2024. "Simultaneous Pancreatic and Kidney Transplant in Adult with Autosomal Dominant Polycystic Kidney Disease and Type I Diabetes Mellitus: Post Surgical Events and Genetic Review." Oman Medical Journal. https://doi.org/10.5001/omj.2024.18.
Harvard
Al Alawi, I., Mohammed, E., Al Rahbi, F., Metry, A., Hannawi, S. and Al Salmi, I. (2024) 'Simultaneous Pancreatic and Kidney Transplant in Adult with Autosomal Dominant Polycystic Kidney Disease and Type I Diabetes Mellitus: Post Surgical Events and Genetic Review', Oman Medical Journal. doi:10.5001/omj.2024.18.
Vancouver
Al Alawi I, Mohammed E, Al Rahbi F, Metry A, Hannawi S, Al Salmi I. Simultaneous Pancreatic and Kidney Transplant in Adult with Autosomal Dominant Polycystic Kidney Disease and Type I Diabetes Mellitus: Post Surgical Events and Genetic Review. Oman Medical Journal. 2024. doi:10.5001/omj.2024.18
IEEE
I. Al Alawi, E. Mohammed, F. Al Rahbi, A. Metry, S. Hannawi, and I. Al Salmi, "Simultaneous Pancreatic and Kidney Transplant in Adult with Autosomal Dominant Polycystic Kidney Disease and Type I Diabetes Mellitus: Post Surgical Events and Genetic Review," Oman Medical Journal, 2024, doi: 10.5001/omj.2024.18.