Abstract
No clinical or laboratory data allow a preoperative diagnosis of parathyroid carcinoma and only occasionally does a definitive finding differentiate an adenoma from a carcinoma. We present a case of primary hyperparathyroidism presenting with severe elevation of parathyroid hormone and serum calcium as well as complications. We go on to discuss the case in the light of a literature review. The severity of the elevation of the parathyroid hormone, other biochemical alterations, the presence of skeletal and renal complications and of a neck mass should alert the clinician to a possible parathyroid carcinoma. Radical surgery is the only effective therapy for parathyroid carcinoma, and should always be performed if a preoperative suspicion is entertained.
Publication details
- DOI
- 10.18295/2075-0528.1165
- Journal
- Sultan Qaboos University Medical Journal, 10(1), 94-100
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Al-Fadhli, M., Doi, S. A., Al-Sumait, T., & Basel (2025). Severe Hyperparathyroidism Versus Parathyroid Carcinoma: A clinical dilemma. Sultan Qaboos University Medical Journal, 10(1), 94-100. https://doi.org/10.18295/2075-0528.1165
MLA 9
Al-Fadhli, Mariam, et al. "Severe Hyperparathyroidism Versus Parathyroid Carcinoma: A clinical dilemma." Sultan Qaboos University Medical Journal, vol. 10, no. 1, 2025, pp. 94-100. https://doi.org/10.18295/2075-0528.1165.
Chicago (author–date)
Al-Fadhli, Mariam, Suhail AR Doi, Thomas Al-Sumait, and Basel. 2025. "Severe Hyperparathyroidism Versus Parathyroid Carcinoma: A clinical dilemma." Sultan Qaboos University Medical Journal 10 (1): 94-100. https://doi.org/10.18295/2075-0528.1165.
Harvard
Al-Fadhli, M., Doi, S. A., Al-Sumait, T. and Basel (2025) 'Severe Hyperparathyroidism Versus Parathyroid Carcinoma: A clinical dilemma', Sultan Qaboos University Medical Journal, 10(1), pp. 94-100. doi:10.18295/2075-0528.1165.
Vancouver
Al-Fadhli M, Doi SA, Al-Sumait T, Basel. Severe Hyperparathyroidism Versus Parathyroid Carcinoma: A clinical dilemma. Sultan Qaboos University Medical Journal. 2025;10(1):94-100. doi:10.18295/2075-0528.1165
IEEE
M. Al-Fadhli, S. A. Doi, T. Al-Sumait, and Basel, "Severe Hyperparathyroidism Versus Parathyroid Carcinoma: A clinical dilemma," Sultan Qaboos University Medical Journal, vol. 10, no. 1, pp. 94-100, 2025, doi: 10.18295/2075-0528.1165.