Abstract
Malignant melanoma is predominantly a skin disease but in rare instances it may occur at other sites. A vaginal melanoma is a rare clinical entity and the round cell type is an uncommon variant. Although the present case was clinically diagnosed as a urethral caruncle, on histopathological examination and immunostaining it was diagnosed as a round cell pigmented malignant melanoma. The patient refused radical surgery and was given a full course radiotherapy treatment but died a year later. Malignant vaginal melanoma carries a very poor prognosis even when lesion is localised at the time of presentation. The five-year survival rate ranges from 10–20% with the prognosis being influenced by tumour size. A tumour size ≥3cm has a poor prognosis. Age, mitotic count, stage, and location of the lesion do not influence survival rates.
Publication details
- DOI
- 10.18295/2075-0528.1414
- Journal
- Sultan Qaboos University Medical Journal, 12(4), 508-511
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Chauhan, N., Gaur, D. S., & P., V. (2025). Round Cell Vaginal Malignant Melanoma: A rare entity. Sultan Qaboos University Medical Journal, 12(4), 508-511. https://doi.org/10.18295/2075-0528.1414
MLA 9
Chauhan, Neena, et al. "Round Cell Vaginal Malignant Melanoma: A rare entity." Sultan Qaboos University Medical Journal, vol. 12, no. 4, 2025, pp. 508-511. https://doi.org/10.18295/2075-0528.1414.
Chicago (author–date)
Chauhan, Neena, Dushyant S. Gaur, and Ved P. 2025. "Round Cell Vaginal Malignant Melanoma: A rare entity." Sultan Qaboos University Medical Journal 12 (4): 508-511. https://doi.org/10.18295/2075-0528.1414.
Harvard
Chauhan, N., Gaur, D. S. and P., V. (2025) 'Round Cell Vaginal Malignant Melanoma: A rare entity', Sultan Qaboos University Medical Journal, 12(4), pp. 508-511. doi:10.18295/2075-0528.1414.
Vancouver
Chauhan N, Gaur DS, P. V. Round Cell Vaginal Malignant Melanoma: A rare entity. Sultan Qaboos University Medical Journal. 2025;12(4):508-511. doi:10.18295/2075-0528.1414
IEEE
N. Chauhan, D. S. Gaur, and V. P., "Round Cell Vaginal Malignant Melanoma: A rare entity," Sultan Qaboos University Medical Journal, vol. 12, no. 4, pp. 508-511, 2025, doi: 10.18295/2075-0528.1414.