Abstract
Retinoblastoma (RB) is the most common intraocular malignancy in children. Recently, there have been significant advances made in the molecular pathology and the management of the disease. Last decade has witnessed better understanding of the genetics of RB, the discovery of new tumor markers expressed by the RB tumors, the identification of high-risk histopathological factors following enucleation, and newer methods of treatment including periocular chemotherapy and superselective intraarterial chemotherapy. All these advances have translated in improved survival rates for the affected children, improved rates of eye salvage, and improved visual outcomes. This article briefly reviews these advances.Method of Literature Search: Literature on the Medline database was searched using the PubMed interface. The search strategy included MeSH and natural language terms using the keywords mentioned. Reference lists in retrieved articles and textbooks were also searched for relevant references.
Keywords
Subject
Publication details
- DOI
- 10.4103/0974-620x.91265
- Journal
- Oman Journal of Ophthalmology, 4(3), 108-115
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Khetan, V., Gupta, A., & Gopal, L. (2011). Retinoblastoma: Recent trends A mini review based on published literature. Oman Journal of Ophthalmology, 4(3), 108-115. https://doi.org/10.4103/0974-620x.91265
MLA 9
Khetan, Vikas, et al. "Retinoblastoma: Recent trends A mini review based on published literature." Oman Journal of Ophthalmology, vol. 4, no. 3, 2011, pp. 108-115. https://doi.org/10.4103/0974-620x.91265.
Chicago (author–date)
Khetan, Vikas, Aditi Gupta, and Lingam Gopal. 2011. "Retinoblastoma: Recent trends A mini review based on published literature." Oman Journal of Ophthalmology 4 (3): 108-115. https://doi.org/10.4103/0974-620x.91265.
Harvard
Khetan, V., Gupta, A. and Gopal, L. (2011) 'Retinoblastoma: Recent trends A mini review based on published literature', Oman Journal of Ophthalmology, 4(3), pp. 108-115. doi:10.4103/0974-620x.91265.
Vancouver
Khetan V, Gupta A, Gopal L. Retinoblastoma: Recent trends A mini review based on published literature. Oman Journal of Ophthalmology. 2011;4(3):108-115. doi:10.4103/0974-620x.91265
IEEE
V. Khetan, A. Gupta, and L. Gopal, "Retinoblastoma: Recent trends A mini review based on published literature," Oman Journal of Ophthalmology, vol. 4, no. 3, pp. 108-115, 2011, doi: 10.4103/0974-620x.91265.