Abstract

Posterior reversible encephalopathy syndrome (PRES) is a neurological condition with a combination of clinical and radiological features. Clinical symptoms include headaches, confusion, seizures, disturbed vision or an altered level of consciousness. Classic magnetic resonance imaging (MRI) findings indicate subcortical and cortical oedema, affecting mainly the posterior cerebral region. We report two paediatric cases of PRES with underlying renal diseases presenting at the Sultan Qaboos University Hospital in Muscat, Oman, in April 2010 and August 2011. The first case was an 11-year-old girl diagnosed with systemic lupus erythematosus and the second was a six-and-a-half-year-old boy on peritoneal dialysis due to multi-drug-resistant nephrotic syndrome. Both patients were hypertensive and treated with blood pressure control medications. No residual neurological dysfunction was noted in the patients at a one-year follow-up and at discharge, respectively. The role of hypertension in paediatric PRES cases, among other important risk factors, is emphasised. Additionally, MRI is an important diagnostic and prognostic tool. Prompt diagnosis and aggressive management is fundamental to preventing permanent neurological damage.

Publication details

DOI
10.18295/2075-0528.1717
Journal
Sultan Qaboos University Medical Journal, 15(3), 424-428
Publisher
Sultan Qaboos University
Open access
Gold open access
License
CC BY-ND 4.0

Cite this article

APA 7

El-Naggari, M. A., Al-Nabhani, D., El-Manzalawy, I., Alaa, & Abdelmogheth, A. A. A. (2025). Posterior Reversible Encephalopathy Syndrome in Two Omani Children with Underlying Renal Diseases. Sultan Qaboos University Medical Journal, 15(3), 424-428. https://doi.org/10.18295/2075-0528.1717

MLA 9

El-Naggari, Mohamed A., et al. "Posterior Reversible Encephalopathy Syndrome in Two Omani Children with Underlying Renal Diseases." Sultan Qaboos University Medical Journal, vol. 15, no. 3, 2025, pp. 424-428. https://doi.org/10.18295/2075-0528.1717.

Chicago (author–date)

El-Naggari, Mohamed A., Dana Al-Nabhani, Ibtisam El-Manzalawy, Alaa, and Anas-Alwogud A. Abdelmogheth. 2025. "Posterior Reversible Encephalopathy Syndrome in Two Omani Children with Underlying Renal Diseases." Sultan Qaboos University Medical Journal 15 (3): 424-428. https://doi.org/10.18295/2075-0528.1717.

Harvard

El-Naggari, M. A., Al-Nabhani, D., El-Manzalawy, I., Alaa and Abdelmogheth, A. A. A. (2025) 'Posterior Reversible Encephalopathy Syndrome in Two Omani Children with Underlying Renal Diseases', Sultan Qaboos University Medical Journal, 15(3), pp. 424-428. doi:10.18295/2075-0528.1717.

Vancouver

El-Naggari MA, Al-Nabhani D, El-Manzalawy I, Alaa, Abdelmogheth AAA. Posterior Reversible Encephalopathy Syndrome in Two Omani Children with Underlying Renal Diseases. Sultan Qaboos University Medical Journal. 2025;15(3):424-428. doi:10.18295/2075-0528.1717

IEEE

M. A. El-Naggari, D. Al-Nabhani, I. El-Manzalawy, Alaa, and A. A. A. Abdelmogheth, "Posterior Reversible Encephalopathy Syndrome in Two Omani Children with Underlying Renal Diseases," Sultan Qaboos University Medical Journal, vol. 15, no. 3, pp. 424-428, 2025, doi: 10.18295/2075-0528.1717.