Abstract
Down syndrome (DS) is the most common chromosomal abnormality found in humans. In Oman, the birth prevalence of DS is 2.4 in 1000 (about 120 affected births per year). Underlying compromised cardiopulmonary status and intellectual disabilities predispose these patients to be particularly vulnerable to serious respiratory viral infections. They also tend to have exaggerated cytokine storms due to underlying immune dysregulation. We report our experience with three DS patients who contracted COVID-19 pneumonia and were admitted to our intensive care unit where they were successfully managed and discharged. Patients with DS are highly susceptible to serious outcomes due to COVID-19. They should be given top priority in immunization programs.
Keywords
Publication details
- DOI
- 10.5001/omj.2023.29
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Kajenthiran, R., Paul, J., & Nair, A. (2023). Patients with Down Syndrome and COVID-19 Pneumonia Requiring Ventilatory Support: A Case Series. Oman Medical Journal. https://doi.org/10.5001/omj.2023.29
MLA 9
Kajenthiran, Rasathurai, et al. "Patients with Down Syndrome and COVID-19 Pneumonia Requiring Ventilatory Support: A Case Series." Oman Medical Journal, 2023. https://doi.org/10.5001/omj.2023.29.
Chicago (author–date)
Kajenthiran, Rasathurai, Jacob Paul, and Abhijit Nair. 2023. "Patients with Down Syndrome and COVID-19 Pneumonia Requiring Ventilatory Support: A Case Series." Oman Medical Journal. https://doi.org/10.5001/omj.2023.29.
Harvard
Kajenthiran, R., Paul, J. and Nair, A. (2023) 'Patients with Down Syndrome and COVID-19 Pneumonia Requiring Ventilatory Support: A Case Series', Oman Medical Journal. doi:10.5001/omj.2023.29.
Vancouver
Kajenthiran R, Paul J, Nair A. Patients with Down Syndrome and COVID-19 Pneumonia Requiring Ventilatory Support: A Case Series. Oman Medical Journal. 2023. doi:10.5001/omj.2023.29
IEEE
R. Kajenthiran, J. Paul, and A. Nair, "Patients with Down Syndrome and COVID-19 Pneumonia Requiring Ventilatory Support: A Case Series," Oman Medical Journal, 2023, doi: 10.5001/omj.2023.29.