Abstract
Hyperreactio luteinalis (HL) and ovarian hyperstimulation syndrome during pregnancy are both benign conditions where the ovaries are enlarged with presence of multiple thin-walled cysts. The differential diagnosis is ovarian malignancy. Hyperandrogenism with resultant maternal virilisation could be seen in some cases of HL as well as in androgen secreting tumours. We report a 41-year-old female patient who underwent ovulation induction due to secondary infertility at a high-risk pregnancy unit in Muscat, Oman, in 2022. She had recurrent hospital admission with abdominal pain and large multicystic enlargement of both ovaries. She developed virilisation features by 35 weeks of pregnancy. Lower segment caesarean section was done at 36 weeks gestation for breech presentation with intra-uterine growth restriction. Magnetic resonance imaging confirmed the benign nature of the cysts. Ovarian cysts and hyperandrogenism gradually resolved 3-months post-delivery. Awareness, judicious imaging and close monitoring in such cases can result in live birth and avoid oophorectomies.
Subject
Publication details
- DOI
- 10.18295/squmj.10.2023.064
- Journal
- Sultan Qaboos University Medical Journal, 24(4), 589-592
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Al Ghaithi, I. S., Santhosh, J., Al-Rawahi, T., Al Shabibi, M. S., Al Harthy, N. R., Al Kalbani, J., & Al Hanashi, M. S. (2025). Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report. Sultan Qaboos University Medical Journal, 24(4), 589-592. https://doi.org/10.18295/squmj.10.2023.064
MLA 9
Al Ghaithi, Istaqlal SH, et al. "Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report." Sultan Qaboos University Medical Journal, vol. 24, no. 4, 2025, pp. 589-592. https://doi.org/10.18295/squmj.10.2023.064.
Chicago (author–date)
Al Ghaithi, Istaqlal SH, Jayasree Santhosh, Thuria Al-Rawahi, Maryam S. Al Shabibi, Najat R. Al Harthy, Jokha Al Kalbani, and Maisa SS Al Hanashi. 2025. "Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report." Sultan Qaboos University Medical Journal 24 (4): 589-592. https://doi.org/10.18295/squmj.10.2023.064.
Harvard
Al Ghaithi, I. S., Santhosh, J., Al-Rawahi, T., Al Shabibi, M. S., Al Harthy, N. R., Al Kalbani, J. and Al Hanashi, M. S. (2025) 'Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report', Sultan Qaboos University Medical Journal, 24(4), pp. 589-592. doi:10.18295/squmj.10.2023.064.
Vancouver
Al Ghaithi IS, Santhosh J, Al-Rawahi T, Al Shabibi MS, Al Harthy NR, Al Kalbani J, et al. Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report. Sultan Qaboos University Medical Journal. 2025;24(4):589-592. doi:10.18295/squmj.10.2023.064
IEEE
I. S. Al Ghaithi, J. Santhosh, T. Al-Rawahi, M. S. Al Shabibi, N. R. Al Harthy, J. Al Kalbani, and M. S. Al Hanashi, "Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report," Sultan Qaboos University Medical Journal, vol. 24, no. 4, pp. 589-592, 2025, doi: 10.18295/squmj.10.2023.064.