Abstract
This study outlines a scenario involving unilateral periocular inflammation exhibited resistance to conventional immunomodulatory therapy (IMT) and biologic response modifying agents, which was successfully managed with oral cyclophosphamide monotherapy. A 39-year-old male visited our clinic, expressing discomfort and swelling in his left upper eyelid for six months. All multidisciplinary consultations and imaging yielded normal results. He remained consistently on a dosage of 50 mg oral prednisone. Blood tests yielded results within the normal range or were negative, with the exception of the antinuclear antibody. He did not respond to conventional IMT and biological response modifier agents. Ultimately, the patient began oral cyclophosphamide. One month after commencing cyclophosphamide treatment, the oral prednisone dosage was gradually reduced without any flare-up. oral cyclophosphamide can serve as a valuable treatment for periocular inflammation that does not respond to standard conventional IMT and biologic response modifier agents.
Keywords
Publication details
- DOI
- 10.4103/ojo.ojo_30_24
- Journal
- Oman Journal of Ophthalmology, 17(3), 399-402
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Maleki, A., Anesi, S. D., Chang, P. Y., & Foster, C. S. (2024). Oral cyclophosphamide treatment for clinical periocular inflammation of unknown origin. Oman Journal of Ophthalmology, 17(3), 399-402. https://doi.org/10.4103/ojo.ojo_30_24
MLA 9
Maleki, Arash, et al. "Oral cyclophosphamide treatment for clinical periocular inflammation of unknown origin." Oman Journal of Ophthalmology, vol. 17, no. 3, 2024, pp. 399-402. https://doi.org/10.4103/ojo.ojo_30_24.
Chicago (author–date)
Maleki, Arash, Stephen D Anesi, Peter Y Chang, and C Stephen Foster. 2024. "Oral cyclophosphamide treatment for clinical periocular inflammation of unknown origin." Oman Journal of Ophthalmology 17 (3): 399-402. https://doi.org/10.4103/ojo.ojo_30_24.
Harvard
Maleki, A., Anesi, S. D., Chang, P. Y. and Foster, C. S. (2024) 'Oral cyclophosphamide treatment for clinical periocular inflammation of unknown origin', Oman Journal of Ophthalmology, 17(3), pp. 399-402. doi:10.4103/ojo.ojo_30_24.
Vancouver
Maleki A, Anesi SD, Chang PY, Foster CS. Oral cyclophosphamide treatment for clinical periocular inflammation of unknown origin. Oman Journal of Ophthalmology. 2024;17(3):399-402. doi:10.4103/ojo.ojo_30_24
IEEE
A. Maleki, S. D. Anesi, P. Y. Chang, and C. S. Foster, "Oral cyclophosphamide treatment for clinical periocular inflammation of unknown origin," Oman Journal of Ophthalmology, vol. 17, no. 3, pp. 399-402, 2024, doi: 10.4103/ojo.ojo_30_24.