Abstract
Amyloidosis is a disorder characterised by the extracellular deposition of amyloid, a fibrillary protein, in various organs such as the lungs. Pulmonary nodular amyloidosis can mimic other lung conditions that present with pulmonary nodules, such as metastasis, sarcoidosis and hyalinising granuloma. We report a 60-year-old man who presented to the Royal Hospital, Muscat, Oman, in 2017 with a history of shortness of breath upon exertion, orthopnoea and bilateral lower limb swelling. A chest X-ray showed bilateral nodular opacities. Enhanced chest computed tomography revealed bilateral pulmonary nodules with a predominantly perilymphatic and subpleural distribution, giving the impression of a neoplastic nodule. A histopathological examination of biopsied lung tissue confirmed a diagnosis of nodular pulmonary amyloidosis.
Publication details
- DOI
- 10.18295/squmj.2018.18.03.023
- Journal
- Sultan Qaboos University Medical Journal, 18(3), e390-393
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Al Umairi, R. S., Al Lawati, F., & M., F. (2025). Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature. Sultan Qaboos University Medical Journal, 18(3), e390-393. https://doi.org/10.18295/squmj.2018.18.03.023
MLA 9
Al Umairi, Rashid S., et al. "Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature." Sultan Qaboos University Medical Journal, vol. 18, no. 3, 2025, pp. e390-393. https://doi.org/10.18295/squmj.2018.18.03.023.
Chicago (author–date)
Al Umairi, Rashid S., Fatma Al Lawati, and Fadhila M. 2025. "Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature." Sultan Qaboos University Medical Journal 18 (3): e390-393. https://doi.org/10.18295/squmj.2018.18.03.023.
Harvard
Al Umairi, R. S., Al Lawati, F. and M., F. (2025) 'Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature', Sultan Qaboos University Medical Journal, 18(3), pp. e390-393. doi:10.18295/squmj.2018.18.03.023.
Vancouver
Al Umairi RS, Al Lawati F, M. F. Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature. Sultan Qaboos University Medical Journal. 2025;18(3):e390-393. doi:10.18295/squmj.2018.18.03.023
IEEE
R. S. Al Umairi, F. Al Lawati, and F. M., "Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature," Sultan Qaboos University Medical Journal, vol. 18, no. 3, pp. e390-393, 2025, doi: 10.18295/squmj.2018.18.03.023.